Extracellular nucleotides, such as adenosine triphosphate (ATP), are released from host
cells including nerve termini, immune cells, injured or dead cells, and the commensal …

ATP is one of the most widely distributed extracellular signaling molecules, regulating many
physiological and pathological processes via activation of purinergic receptors. Extracellular …

Allergic asthma is a chronic airway inflammatory response to different triggers like inhaled
allergens. Excessive ATP in fluids from patients with asthma is considered an inflammatory …

Calcium homeostasis modulator 1 (CALHM1) is a voltage-gated ATP release channel that
plays an important role in neural gustatory signaling and the pathogenesis of Alzheimer's …

Since the late 1970s, there has been an alarming increase in the incidence of asthma and
its morbidity and mortality. Acute obstruction and inflammation of allergic asthmatic airways …

Extracellular ATP works as an autocrine and/or paracrine signaling molecule by activating
plasma membrane-localized purinergic receptors. Stimulation of purinergic P2X7 receptor …

Adenosine 5′-triphosphate (ATP) is an ubiquitous co-transmitter in the vertebrate brain.
ATP itself, as well as its breakdown products ADP and adenosine are involved in synaptic …

T cells form an immune synapse (IS) with antigen-presenting cells (APCs) to detect antigens
that match their TCR. Mitochondria, pannexin-1 (panx1) channels, and P2X4 receptors …

Extracellular ATP (eATP) and P2 receptors are novel emerging regulators of T-lymphocyte
responses. Cellular ATP is released via multiple pathways and accumulates at sites of tissue …

Calcium homeostasis modulator 1 (CALHM1) is a voltage-and Ca 2+-gated ATP channel
that plays an important role in neuronal signaling. However, as the previously reported …