In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Extracellular vesicles (EVs) have received increasing attention over the last two decades.
Initially, they were considered as just a garbage disposal tool; however, it has progressively …

The modulation of canonical macroautophagy/autophagy for therapeutic benefit is an
emerging strategy of medical and pharmaceutical interest. Many drugs act to inhibit …

Abstract Treatment with nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with
various side effects, including cardiovascular and hepatic disorders. Studies suggest that …

The concept of lysosomotropic agents significantly changed numerous aspects of cellular
biochemistry, biochemical pharmacology, and clinical medicine. In the present review, we …

Drug-induced gastrointestinal toxicity (GIT) is a common treatment-emergent adverse event
that can negatively impact dosing, thereby limiting efficacy and treatment options for …

Background Rab37-mediated exocytosis of tissue inhibitor of metalloproteinase 1 (TIMP1),
an inflammatory cytokine, under serum-depleted conditions which leads to suppression of …

Objective (s): Abnormal lung cell death including autophagy and apoptosis is the central
feature in acute lung injury (ALI). To identify the cellular mechanisms and the chronology by …

Amiodarone (AD) is an iodinated benzofuran derivative, especially known for its
antiarrhythmic properties. It exerts serious side‐effects even in patients receiving low doses …

Amiodarone is a widely used antiarrhythmic drug that can cause the development of
steatohepatitis as well as liver fibrosis and cirrhosis. The molecular mechanisms of …