Links between inflammatory bowel disease and chronic obstructive pulmonary disease
Inflammatory bowel disease (IBD) and chronic obstructive pulmonary disease (COPD) are
chronic inflammatory diseases of the gastrointestinal and respiratory tracts, respectively …
chronic inflammatory diseases of the gastrointestinal and respiratory tracts, respectively …
Gut microbiota-produced tryptamine activates an epithelial G-protein-coupled receptor to increase colonic secretion
Y Bhattarai, BB Williams, EJ Battaglioli, WR Whitaker… - Cell host & …, 2018 - cell.com
Tryptamine, a tryptophan-derived monoamine similar to 5-hydroxytryptamine (5-HT), is
produced by gut bacteria and is abundant in human and rodent feces. However, the …
produced by gut bacteria and is abundant in human and rodent feces. However, the …
The aryl hydrocarbon receptor in the crossroad of signalling networks with therapeutic value
The aryl hydrocarbon receptor (AhR) is well-known for its major contributions to the cellular
responses against environmental toxins and carcinogens. Notably, AhR has also emerged …
responses against environmental toxins and carcinogens. Notably, AhR has also emerged …
Identification of gene expression profiles associated with an increased risk of post-operative recurrence in Crohn's disease
Abstract Background and Aims Ileocolonic resection is frequently needed in the course of
Crohn's disease [CD] treatment and post-operative recurrence is extremely common. Our …
Crohn's disease [CD] treatment and post-operative recurrence is extremely common. Our …
Epigenetic regulations of AhR in the aspect of immunomodulation
A Wajda, J Łapczuk-Romańska… - International Journal of …, 2020 - mdpi.com
Environmental factors contribute to autoimmune disease manifestation, and as regarded
today, AhR has become an important factor in studies of immunomodulation. Besides …
today, AhR has become an important factor in studies of immunomodulation. Besides …
Evolution of hominin detoxification: Neanderthal and modern human Ah receptor respond similarly to TCDD
JM Aarts, GM Alink, HJ Franssen… - Molecular Biology and …, 2021 - academic.oup.com
In studies of hominin adaptations to fire use, the role of the aryl hydrocarbon receptor (AHR)
in the evolution of detoxification has been highlighted, including statements that the modern …
in the evolution of detoxification has been highlighted, including statements that the modern …
AHR gene expression and the polymorphism rs2066853 are associated with clinicopathological parameters in colorectal carcinoma
T Cheng, SMK Gamage, D Hewage, CT Lu, S Aktar… - Human Pathology, 2022 - Elsevier
The relationship between red and processed meat and its risk toward colorectal carcinoma
(CRC) is not fully explored in literature. Polycyclic aromatic hydrocarbons (PAHs) are …
(CRC) is not fully explored in literature. Polycyclic aromatic hydrocarbons (PAHs) are …
Aryl hydrocarbon receptor polymorphisms are associated with dry skin phenotypes in Chinese patients with atopic dermatitis
ZZ Li, WL Zhong, H Hu, XF Chen… - Clinical and …, 2019 - academic.oup.com
Background Epidermal barrier dysfunction is the initial event in the development of atopic
dermatitis (AD). Recent studies have identified a crucial role for the aryl hydrocarbon …
dermatitis (AD). Recent studies have identified a crucial role for the aryl hydrocarbon …
Evaluation of variation in genes of the arylhydrocarbon receptor pathway for an association with multiple sclerosis
N Zorlu, S Hoffjan, A Haghikia, IV Deyneko… - Journal of …, 2019 - Elsevier
The aryl hydrocarbon receptor (AhR) contributes to immune regulation in autoimmune
diseases such as multiple sclerosis (MS). Analysis of selected polymorphisms in AhR …
diseases such as multiple sclerosis (MS). Analysis of selected polymorphisms in AhR …
Association of Crohn's disease with aryl hydrocarbon receptor gene polymorphisms in patients from Southeast China
C Wu, Q Lin, S Ying, J Luo, W Hong, Z Lin… - Immunological …, 2019 - Taylor & Francis
Aims The aryl hydrocarbon receptor (AhR) plays a pivotal role in regulating the innate and
the acquired immune systems. The present study aimed to investigate the association of …
the acquired immune systems. The present study aimed to investigate the association of …