Introduction: Coronary thrombosis is a frequent cause of death and myocardial infarction
most often explained by superimposition of a platelet-rich thrombus on existing coronary …

The concept of “pharmacogenetics” addresses genetically determined variation in how
individuals respond to drugs. Accordingly, specific genetic variants have been suggested as …

Background: Previous studies have demonstrated considerable variation in the antiplatelet
effect of aspirin. Objectives: To investigate the impact of platelet turnover on the antiplatelet …

Objective To evaluate the effect of proton pump inhibitors (PPIs) on the platelet response to
aspirin in patients with coronary artery disease (CAD). Design Case–control study. Patients …

INTRODUCTION: Platelet function testing in whole blood is widely used to evaluate the
effect of antiplatelet agents, but it is not known whether results are affected by whole blood …

Individualised antiplatelet therapy and platelet function testing have attracted considerable
clinical interest, but several aspects of test performance have not been thoroughly …

INTRODUCTION: Diabetes mellitus is complicated by accelerated atherosclerosis, resulting
in an increased risk of coronary artery disease (CAD) and thrombosis. Despite the proven …

Objectives: This study sought to evaluate the platelet response to aspirin and the immature
platelet fraction in patients with previous stent thrombosis (ST). Background: ST is a …

Newly produced platelets are present in the acute phase of ST-elevation myocardial
infarction (STEMI). This may influence the antiplatelet effect of aspirin and clopidogrel …

Antiplatelet effect of aspirin in patients with coronary artery disease Page 1 PHD THESIS
DANISH MEDICAL JOURNAL DANISH MEDICAL JOURNAL 1 This review has been accepted …