The use of alternative strategies for enhanced nanoparticle delivery to solid tumors

M Izci, C Maksoudian, BB Manshian… - Chemical …, 2021 - ACS Publications
Nanomaterial (NM) delivery to solid tumors has been the focus of intense research for over a
decade. Classically, scientists have tried to improve NM delivery by employing passive or …

Biomaterial-mediated internal radioisotope therapy

P Pei, T Liu, W Shen, Z Liu, K Yang - Materials Horizons, 2021 - pubs.rsc.org
Radiation therapy (RT), including external beam radiotherapy (EBRT) and internal
radioisotope therapy (RIT), has been an indispensable strategy for cancer therapy in clinical …

Systematic review of cancer targeting by nanoparticles revealed a global association between accumulation in tumors and spleen

AS Drozdov, PI Nikitin, JM Rozenberg - International journal of molecular …, 2021 - mdpi.com
Active targeting of nanoparticles toward tumors is one of the most rapidly developing topics
in nanomedicine. Typically, this strategy involves the addition of cancer-targeting …

RGD-engineered nanoparticles as an innovative drug delivery system in cancer therapy

M Sanati, AR Afshari, S Aminyavari… - Journal of Drug Delivery …, 2023 - Elsevier
The poor efficiency and drastic adverse effects of current cancer therapies entail a radical
shift in treatment paradigms, which require developing cutting-edge therapeutics in …

Radiolabeled gold nanoparticles for imaging and therapy of cancer

F Silva, MP Cabral Campello, A Paulo - Materials, 2020 - mdpi.com
In the Last decades, nanotechnology has provided novel and alternative methodologies and
tools in the field of medical oncology, in order to tackle the issues regarding the control and …

Nano-therapeutics for modulating the tumour microenvironment: Design, development, and clinical translation

S Adityan, M Tran, C Bhavsar, SY Wu - Journal of controlled release, 2020 - Elsevier
Nanoparticles (NPs) that permit active targeting promise to play a key role in cancer therapy
moving forward. However, in order to successfully advance into clinic, these delivery …

A pH/ROS-responsive, tumor-targeted drug delivery system based on carboxymethyl chitin gated hollow mesoporous silica nanoparticles for anti-tumor chemotherapy

X Ding, W Yu, Y Wan, M Yang, C Hua, N Peng… - Carbohydrate …, 2020 - Elsevier
A new nanosystem was prepared by coating ROS-cleavable thioketal (TK) bonded hollow
mesoporous silica nanoparticles with carboxymethyl chitin via electrostatic interaction and …

[HTML][HTML] Gold nanoparticles meet medical radionuclides

N Daems, C Michiels, S Lucas, S Baatout… - Nuclear Medicine and …, 2021 - Elsevier
Thanks to their unique optical and physicochemical properties, gold nanoparticles have
gained increased interest as radiosensitizing, photothermal therapy and optical imaging …

Advances in the design of amino acid and peptide synthesized gold nanoparticles for their applications

A Rai, S Seena, T Gagliardi, PJ Palma - Advances in Colloid and Interface …, 2023 - Elsevier
The field of therapeutics and diagnostics is advanced by nanotechnology-based
approaches including the spatial-temporal release of drugs, targeted delivery, enhanced …

The peptide functionalized inorganic nanoparticles for cancer-related bioanalytical and biomedical applications

X Li, M Jian, Y Sun, Q Zhu, Z Wang - Molecules, 2021 - mdpi.com
In order to improve their bioapplications, inorganic nanoparticles (NPs) are usually
functionalized with specific biomolecules. Peptides with short amino acid sequences have …