Preparation and application of pH-responsive drug delivery systems

H Ding, P Tan, S Fu, X Tian, H Zhang, X Ma… - Journal of Controlled …, 2022 - Elsevier
Microenvironment-responsive drug delivery systems (DDSs) can achieve targeted drug
delivery, reduce drug side effects and improve drug efficacies. Among them, pH-responsive …

[HTML][HTML] Nanoparticle surface functionalization: how to improve biocompatibility and cellular internalization

G Sanità, B Carrese, A Lamberti - Frontiers in molecular biosciences, 2020 - frontiersin.org
The use of nanoparticles (NP) in diagnosis and treatment of many human diseases,
including cancer, is of increasing interest. However, cytotoxic effects of NPs on cells and the …

[HTML][HTML] Metal–curcumin complexes in therapeutics: an approach to enhance pharmacological effects of curcumin

S Prasad, D DuBourdieu, A Srivastava… - International journal of …, 2021 - mdpi.com
Curcumin, an active component of the rhizome turmeric, has gained much attention as a
plant-based compound with pleiotropic pharmacological properties. It possesses anti …

[HTML][HTML] PLGA-based nanomedicine: history of advancement and development in clinical applications of multiple diseases

HO Alsaab, FD Alharbi, AS Alhibs, NB Alanazi… - Pharmaceutics, 2022 - mdpi.com
Research on the use of biodegradable polymers for drug delivery has been ongoing since
they were first used as bioresorbable surgical devices in the 1980s. For tissue engineering …

[HTML][HTML] Development of nanotechnology-mediated precision radiotherapy for anti-metastasis and radioprotection

Y Pan, W Tang, W Fan, J Zhang, X Chen - Chemical Society Reviews, 2022 - pubs.rsc.org
Radiotherapy (RT), including external beam RT and internal radiation therapy, uses high-
energy ionizing radiation to kill tumor cells. However, ionizing radiation inevitably damages …

Branched polymer‐based redox/enzyme‐activatable photodynamic nanoagent to trigger STING‐dependent immune responses for enhanced therapeutic effect

Q Luo, Z Duan, X Li, L Gu, L Ren, H Zhu… - Advanced Functional …, 2022 - Wiley Online Library
Immune response in the tumor microenvironment (TME) is an essential therapeutic factor for
antitumor therapy. Herein, to improve immunostimulatory effects, photodynamic therapy …

Nano encapsulated curcumin: and its potential for biomedical applications

Y Chen, Y Lu, RJ Lee, G Xiang - International Journal of …, 2020 - Taylor & Francis
Curcumin, a yellow-colored polyphenol extracted from the rhizome of turmeric root, is
commonly used as a spice and nutritional supplement. It exhibits many pharmacological …

Curcumin delivery and co-delivery based on nanomaterials as an effective approach for cancer therapy

M Pourmadadi, P Abbasi, MM Eshaghi… - Journal of Drug Delivery …, 2022 - Elsevier
Throughout the world, cancer is one of the main causes of mortality, threatening the public
health in many countries. As a result, cancer therapy researchers are paying increasing …

Curcumin–cisplatin chemotherapy: A novel strategy in promoting chemotherapy efficacy and reducing side effects

Y Hussain, L Islam, H Khan, R Filosa… - Phytotherapy …, 2021 - Wiley Online Library
The efficacy of chemotherapy in cancer therapy is limited due to resistance, treatment
selectivity, and severe adverse effects. Immunotherapy, chemotherapy, targeted therapy …

[HTML][HTML] Target identification of natural medicine with chemical proteomics approach: probe synthesis, target fishing and protein identification

X Chen, Y Wang, N Ma, J Tian, Y Shao, B Zhu… - … and Targeted Therapy, 2020 - nature.com
Natural products are an important source of new drugs for the treatment of various diseases.
However, developing natural product-based new medicines through random moiety …