Antibiotic‐free antibacterial strategies enabled by nanomaterials: progress and perspectives
Bacterial infection is one of the top ten leading causes of death globally and the worst killer
in low‐income countries. The overuse of antibiotics leads to ever‐increasing antibiotic …
in low‐income countries. The overuse of antibiotics leads to ever‐increasing antibiotic …
[HTML][HTML] The demand for new antibiotics: antimicrobial peptides, nanoparticles, and combinatorial therapies as future strategies in antibacterial agent design
A León-Buitimea, CR Garza-Cárdenas… - Frontiers in …, 2020 - frontiersin.org
The inappropriate use of antibiotics and an inadequate control of infections have led to the
emergence of resistant strains which represent a major threat to public health and the global …
emergence of resistant strains which represent a major threat to public health and the global …
Targeting microbial biofilms: current and prospective therapeutic strategies
H Koo, RN Allan, RP Howlin, P Stoodley… - Nature Reviews …, 2017 - nature.com
Biofilm formation is a key virulence factor for a wide range of microorganisms that cause
chronic infections. The multifactorial nature of biofilm development and drug tolerance …
chronic infections. The multifactorial nature of biofilm development and drug tolerance …
Antimicrobial hybrid amphiphile via dynamic covalent bonds enables bacterial biofilm dispersal and bacteria eradication
To tackle the problems caused by bacterial biofilms, herein, this study reports an
antimicrobial hybrid amphiphile (aHA) via dynamic covalent bonds for eradicating …
antimicrobial hybrid amphiphile (aHA) via dynamic covalent bonds for eradicating …
Nanoparticle-based local antimicrobial drug delivery
Despite the wide success of antibiotics in modern medicine, the treatment of bacterial
infections still faces critical challenges, especially due to the rapid emergence of antibiotic …
infections still faces critical challenges, especially due to the rapid emergence of antibiotic …
[HTML][HTML] The complex relationship between virulence and antibiotic resistance
Antibiotic resistance, prompted by the overuse of antimicrobial agents, may arise from a
variety of mechanisms, particularly horizontal gene transfer of virulence and antibiotic …
variety of mechanisms, particularly horizontal gene transfer of virulence and antibiotic …
[HTML][HTML] Synthesis of a covalent organic framework with hetero-environmental pores and its medicine co-delivery application
W Ji, P Zhang, G Feng, YZ Cheng, TX Wang… - Nature …, 2023 - nature.com
The topology type and the functionalization of pores play an important role in regulating the
performance of covalent organic frameworks. Herein, we designed and synthesized the …
performance of covalent organic frameworks. Herein, we designed and synthesized the …
Electrospray for generation of drug delivery and vaccine particles applied in vitro and in vivo
Also known as electrospray, electrohydrodynamic atomization has been used extensively in
the last 15 years to develop polymer-based particles for drug delivery in cell and animal …
the last 15 years to develop polymer-based particles for drug delivery in cell and animal …
Antibacterial, cytocompatible, sustainably sourced: cellulose membranes with bifunctional peptides for advanced wound dressings
R Weishaupt, JN Zünd, L Heuberger… - Advanced …, 2020 - Wiley Online Library
Progressive antibiotic resistance is a serious condition adding to the challenges associated
with skin wound treatment, and antibacterial wound dressings with alternatives to antibiotics …
with skin wound treatment, and antibacterial wound dressings with alternatives to antibiotics …
Liposomal delivery systems and their applications against Staphylococcus aureus and methicillin-resistant Staphylococcus aureus
Liposomal delivery systems have been widely explored for targeting superbugs such as S.
aureus and MRSA, overcoming antimicrobial resistance associated with conventional …
aureus and MRSA, overcoming antimicrobial resistance associated with conventional …