Nonsteroidal anti‐inflammatory drugs (NSAIDs), the medications most commonly used for
treating pain and inflammation, are the main triggers of drug hypersensitivity reactions. The …

Asthma is a common complex disease of the airways. Genome-wide association studies
(GWASs) of asthma have identified many risk alleles and loci that have been replicated in …

Asthma is a heterogeneous disease with many phenotypes, and age at disease onset is an
important factor in separating the phenotypes. Genetic factors, atopy, and early respiratory …

The concept of gene-environment (GxE) interactions has dramatically evolved in the last
century and has now become a central theme in studies that assess the causes of human …

Although sequencing a single human genome was a monumental effort a decade ago, more
than 1000 genomes have now been sequenced. The task ahead lies in transforming this …

Off‐target adverse drug reactions (ADRs) are associated with significant morbidity and costs
to the healthcare system, and their occurrence is not predictable based on the known …

Researchers have long been presented with the challenge imposed by the role of genetic
heterogeneity in drug response. For many years, Pharmacogenomics and …

Non‐steroidal anti‐inflammatory drugs (NSAID s) are the medications most frequently
involved in hypersensitivity drug reactions. Because NSAID s are prescribed for many …

Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the medicines most frequently
prescribed worldwide, many of which are available over the counter. 1 NSAIDs induce a …

Aspirin-exacerbated respiratory disease (AERD) is a nonallergic clinical syndrome
characterized by a severe decline in forced expiratory volume in one second (FEV1) …