Obesity is a major risk factor for the development of insulin resistance and type 2 diabetes.
The exact mechanism by which adipose tissue induces insulin resistance is still unclear. It …

The increase in free fatty acid flux resulting from increased lipolysis secondary to adipose-
tissue insulin resistance induces or aggravates insulin resistance in liver and muscle …

Background and Objectives: By studying cardiometabolic risk factors in children born after
maternal biliopancreatic diversion bariatric surgery (AMS) compared with those in children …

To study the effects of fatty acids and the involvement of the Toll‐like receptor‐4/nuclear
factor‐κB (TLR‐4/NF‐κB) pathway with respect to the secretion of adipokines from …

OBJECTIVES: To describe the pathophysiological mechanisms by which obesity increases
the propensity to thrombosis, the leading cause of death in the Western World, with …

For many years adipose tissue was viewed as the site where excess energy was stored, in
the form of triglycerides (TGs), and where that energy, when needed elsewhere in the body …

White adipose tissue, previously regarded as a passive lipid storage site, is now viewed as a
dynamic tissue. It has the capacity to actively communicate by sending and receiving …

Insulin resistant states are commonly associated with an atherogenic dyslipidemia that
contributes to significantly higher risk of atherosclerosis and cardiovascular disease. Indeed …

Resistin is a member of a class of cysteine-rich proteins collectively termed resistin-like
molecules. Resistin has been implicated in the pathogenesis of obesity-mediated insulin …

The most common pathology associated with obesity is insulin resistance, which results in
the onset of type 2 diabetes mellitus. Several studies have implicated the mammalian target …