[HTML][HTML] SARS-CoV-2-specific immune response and the pathogenesis of COVID-19

E Gusev, A Sarapultsev, L Solomatina… - International journal of …, 2022 - mdpi.com
The review aims to consolidate research findings on the molecular mechanisms and
virulence and pathogenicity characteristics of coronavirus disease (COVID-19) causative …

[HTML][HTML] Atherosclerosis and inflammation: insights from the theory of general pathological processes

E Gusev, A Sarapultsev - International Journal of Molecular Sciences, 2023 - mdpi.com
Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …

[HTML][HTML] Inflammation: A new look at an old problem

E Gusev, Y Zhuravleva - International Journal of Molecular Sciences, 2022 - mdpi.com
Pro-inflammatory stress is inherent in any cells that are subject to damage or threat of
damage. It is defined by a number of universal components, including oxidative stress …

The preventive effect of Glycyrrhiza polysaccharide on lipopolysaccharide-induced acute colitis in mice by modulating gut microbial communities

X Wei, N Li, X Wu, G Cao, H Qiao, J Wang… - International Journal of …, 2023 - Elsevier
Acute colitis is characterised by an unpredictable onset and causes intestinal flora
imbalance together with microbial migration, which leads to complex parenteral diseases …

[HTML][HTML] Theophylline: Old drug in a new light, application in COVID-19 through computational studies

LM Montaño, B Sommer, JC Gomez-Verjan… - International Journal of …, 2022 - mdpi.com
Theophylline (3-methyxanthine) is a historically prominent drug used to treat respiratory
diseases, alone or in combination with other drugs. The rapid onset of the COVID-19 …

[HTML][HTML] Catalpol attenuates oxidative stress and inflammation via mechanisms involving sirtuin-1 activation and NF-κB inhibition in experimentally-induced chronic …

NE Zaaba, S Al-Salam, S Beegam, O Elzaki, J Yasin… - Nutrients, 2023 - mdpi.com
Chronic kidney disease (CKD) is a stealthy disease, and its development is linked to
mechanisms including inflammation and oxidative stress. Catalpol (CAT), an iridoid …

[HTML][HTML] JAK-STAT signaling in inflammation and stress-related diseases: implications for therapeutic interventions

A Sarapultsev, E Gusev, M Komelkova, I Utepova… - Molecular …, 2023 - Springer
The Janus kinase-signal transducer and transcription activator pathway (JAK-STAT) serves
as a cornerstone in cellular signaling, regulating physiological and pathological processes …

[HTML][HTML] Acute and chronic systemic inflammation: features and differences in the pathogenesis, and integral criteria for verification and differentiation

N Zotova, Y Zhuravleva, V Chereshnev… - International Journal of …, 2023 - mdpi.com
Currently, there is rationale for separating the systemic manifestations of classical
inflammation from systemic inflammation (SI) itself as an independent form of the general …

[HTML][HTML] The nuclear factor kappa B signaling pathway is a master regulator of renal fibrosis

N Ren, WF Wang, L Zou, YL Zhao, H Miao… - Frontiers in …, 2024 - frontiersin.org
Renal fibrosis is increasingly recognized as a global public health problem. Acute kidney
injury (AKI) and chronic kidney disease (CKD) both result in renal fibrosis. Oxidative stress …

[HTML][HTML] Urinalysis, but not blood biochemistry, detects the early renal impairment in patients with COVID-19

H Zhou, Z Zhang, M Dobrinina, Y Dong, Z Kang… - Diagnostics, 2022 - mdpi.com
Background: Coronavirus 2019 (COVID-19), caused by the severe acute respiratory
syndrome coronavirus (SARS-CoV-2), has created a tremendous economic and medical …