Differential inflammatory response to Helicobacter pylori infection: etiology and clinical outcomes

JR White, JA Winter, K Robinson - Journal of inflammation …, 2015 - Taylor & Francis
The bacterial pathogen Helicobacter pylori commonly colonizes the human gastric mucosa
during early childhood and persists throughout life. The organism has evolved multiple …

[HTML][HTML] Host pathogen interactions in Helicobacter pylori related gastric cancer

M Chmiela, Z Karwowska, W Gonciarz… - World journal of …, 2017 - ncbi.nlm.nih.gov
Abstract Helicobacter pylori (H. pylori), discovered in 1982, is a microaerophilic, spiral-
shaped gram-negative bacterium that is able to colonize the human stomach. Nearly half of …

Helicobacter pylori actively suppresses innate immune nucleic acid receptors

SDR Dooyema, JM Noto, LE Wroblewski… - Gut …, 2022 - Taylor & Francis
Chronic mucosal pathogens have evolved multiple strategies to manipulate the host
immune response; consequently, microbes contribute to the development of> 2 million …

Pathogenic H elicobacter pylori strains translocate DNA and activate TLR9 via the cancer-associated cag type IV secretion system

MG Varga, CL Shaffer, JC Sierra, G Suarez… - Oncogene, 2016 - nature.com
Helicobacter pylori (H. pylori) is the strongest identified risk factor for gastric cancer, the third
most common cause of cancer-related death worldwide. An H. pylori constituent that …

A literature review on the potential clinical implications of streptococci in gastric cancer

M Zi, Y Zhang, C Hu, S Zhang, J Chen, L Yuan… - Frontiers in …, 2022 - frontiersin.org
Streptococcus is widely found in nature and the human body, and most species are not
pathogenic. In recent years, studies have found that Streptococcus is associated with gastric …

Genetic host factors in Helicobacter pylori-induced carcinogenesis: Emerging new paradigms

MC Mommersteeg, J Yu, MP Peppelenbosch… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Helicobacter Pylori is a gram negative rod shaped microaerophilic bacterium that colonizes
the stomach of approximately half the world's population. Infection with c may cause chronic …

STAT3-mediated upregulation of the AIM2 DNA sensor links innate immunity with cell migration to promote epithelial tumourigenesis

RE Dawson, V Deswaerte, AC West, K Tang, AJ West… - Gut, 2022 - gut.bmj.com
Objective The absent in melanoma 2 (AIM2) cytosolic pattern recognition receptor and DNA
sensor promotes the pathogenesis of autoimmune and chronic inflammatory diseases via …

Nanoparticle-based phototriggered cancer immunotherapy and its domino effect in the tumor microenvironment

SK Rajendrakumar, S Uthaman, CS Cho… - …, 2018 - ACS Publications
Immune system evasion by cancer cells is one of the hallmarks of cancers, and it occurs with
the support of tumor-associated immune cells (TICs) in the tumor microenvironment that …

Helicobacter pylori and gastric cancer progression

MA Senchukova - Current Microbiology, 2022 - Springer
Gastric cancer (GC) remains the fifth most common malignant tumor and the third leading
cause of cancer death, despite the decline in incidence and mortality worldwide over the …

Current progress and challenges of immunotherapy in gastric cancer: A focus on CAR-T cells therapeutic approach

M Entezam, MJ Sanaei, Y Mirzaei, AH Mer… - Life sciences, 2023 - Elsevier
Gastric cancer (GC) is a severe malignancy, accounting for the third most common cancer
death worldwide. Despite the development of chemo-radiation therapy, there has not been …