Biological markers of exposure to organophosphorus nerve agents

RM Black, RW Read - Archives of toxicology, 2013 - Springer
Organophosphorus nerve agents are the most toxic chemical warfare agents that are known
to have been produced, stockpiled and weaponised. Their development, production …

Environmental exposure to organophosphorus nerve agents

S Vucinic, B Antonijevic, AM Tsatsakis… - Environmental …, 2017 - Elsevier
Exposure to organophosphorus nerve agents, the most deadly chemical warfare agents, is
possible in a variety of situations, such as destruction of chemical warfare agents, terrorist …

Caramiphen edisylate as adjunct to standard therapy attenuates soman-induced seizures and cognitive deficits in rats

MK Schultz, LKM Wright, M de Araujo Furtado… - Neurotoxicology and …, 2014 - Elsevier
The progression of epileptiform activity following soman (GD) exposure is characterized by a
period of excessive cholinergic activity followed by excessive glutamatergic activity resulting …

Gas chromatography-tandem mass spectrometry verification of sulfur mustard exposure in humans through the conversion of protein adducts to free sulfur mustard

SA Young, BR Capacio - Chemical Research in Toxicology, 2020 - ACS Publications
Exposures to sulfur mustard (HD; bis (2-chloroethyll) sulfide) are well-known to result in the
formation of adducts with free aspartate and glutamate residues of plasma proteins …

Advice on chemical weapons sample stability and storage provided by the Scientific Advisory Board of the Organisation for the Prohibition of Chemical Weapons to …

CM Timperley, JE Forman, M Abdollahi, AS Al-Amri… - Talanta, 2018 - Elsevier
Abstract The Scientific Advisory Board (SAB) of the Organisation for the Prohibition of
Chemical Weapons (OPCW) has provided advice on the long-term storage and stability of …

The Application of a single-column GC–MS-MS method for the rapid analysis of chemical warfare agents and breakdown products

SA Young, BR Capacio - Journal of analytical toxicology, 2019 - academic.oup.com
The development of one comprehensive gas chromatographic-triple quadrupole mass
spectrometric (GC–MS-MS) method for the analysis of nerve agents and their breakdown …

Determination of nerve agent metabolites by ultraviolet femtosecond laser ionization mass spectrometry

A Hamachi, T Imasaka, H Nakamura, A Li… - Analytical …, 2017 - ACS Publications
Nerve agent metabolites, ie, isopropyl methylphosphonic acid (IMPA) and pinacolyl
methylphosphonic acid (PMPA), were derivatized by reacting them with 2, 3, 4, 5, 6 …

Developing health-based pre-planning clearance goals for airport remediation following a chemical terrorist attack: decision criteria for multipathway exposure routes

A Watson, F Dolislager, L Hall, E Raber… - … and ecological risk …, 2011 - Taylor & Francis
In the event of a chemical terrorist attack on a transportation hub, post-event remediation
and restoration activities necessary to attain unrestricted facility re-use and re-entry could …

Characterization, chemical phase identification, and performance evaluation of omnipotent polymers used in the manufacturing of personal protective garments

TE Lefakane, PP Ndibewu… - Polymers Research …, 2015 - search.proquest.com
In the present work, comprehensive physico-chemical properties investigations of
permeation studies, tensile strength, spectroscopy (FTIR) and microscopy (SEM) of four …

Assessment of nerve agent exposure: existing and emerging methods

JP Langenberg, MJ van der Schans, D Noort - Bioanalysis, 2009 - Future Science
The perceived threat of the use of nerve agents by terrorists against civilian targets implies
the need for methods for point-of-care (POC) diagnosis. This review presents an overview of …