Immunomodulatory and anti-inflammatory properties of selenium-containing agents: Their role in the regulation of defense mechanisms against COVID-19

VN Mal'tseva, MV Goltyaev, EA Turovsky… - International Journal of …, 2022 - mdpi.com
The review presents the latest data on the role of selenium-containing agents in the
regulation of diseases of the immune system. We mainly considered the contributions of …

Selenium: a double-edged sword for defense and offence in cancer

J Brozmanová, D Mániková, V Vlčková… - Archives of toxicology, 2010 - Springer
Selenium (Se) is an essential dietary component for animals including humans and is
regarded as a protective agent against cancer. Although the mode of anticancer action of Se …

Selenides and diselenides: A review of their anticancer and chemopreventive activity

M Álvarez-Pérez, W Ali, MA Marć, J Handzlik… - Molecules, 2018 - mdpi.com
Selenium and selenocompounds have attracted the attention and the efforts of scientists
worldwide due to their promising potential applications in cancer prevention and/or …

Selenium compounds, apoptosis and other types of cell death: an overview for cancer therapy

C Sanmartín, D Plano, AK Sharma… - International journal of …, 2012 - mdpi.com
Selenium (Se) is an essential trace element involved in different physiological functions of
the human body and plays a role in cancer prevention and treatment. Induction of apoptosis …

Dietary factors and prostate cancer development, progression, and reduction

M Oczkowski, K Dziendzikowska… - Nutrients, 2021 - mdpi.com
Due to the constantly increasing number of cases, prostate cancer has become one of the
most important health problems of modern societies. This review presents the current …

Diphenyl Diselenide and SARS-CoV-2: in silico Exploration of the Mechanisms of Inhibition of Main Protease (Mpro) and Papain-like Protease (PLpro)

FB Omage, A Madabeni, AR Tucci… - Journal of Chemical …, 2023 - ACS Publications
The SARS-CoV-2 pandemic has prompted global efforts to develop therapeutics. The main
protease of SARS-CoV-2 (Mpro) and the papain-like protease (PLpro) are essential for viral …

Design, synthesis, and biological evaluation of novel selenium (Se-NSAID) molecules as anticancer agents

D Plano, DN Karelia, MK Pandey… - Journal of medicinal …, 2016 - ACS Publications
The synthesis and anticancer evaluation of novel selenium-nonsteroidal anti-inflammatory
drug (Se-NSAID) hybrid molecules are reported. The Se-aspirin analogue 8 was identified …

Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells

P Rajendran, E Ho, DE Williams, RH Dashwood - Clinical epigenetics, 2011 - Springer
Genomic instability is a common feature of cancer etiology. This provides an avenue for
therapeutic intervention, since cancer cells are more susceptible than normal cells to DNA …

Organoselenium-catalyzed mild dehydration of aldoximes: An unexpected practical method for organonitrile synthesis

L Yu, H Li, X Zhang, J Ye, J Liu, Q Xu, M Lautens - Organic letters, 2014 - ACS Publications
Areneselenenic acids (ArSeOH), readily generated from diaryl diselenides and H2O2 by in
situ oxidation, were found to be effective and reusable catalysts for dehydration of …

Bimodal actions of selenium essential for antioxidant and toxic pro-oxidant activities: the selenium paradox

KH Lee, D Jeong - Molecular medicine reports, 2012 - spandidos-publications.com
Selenium is an essential biological trace element. Adult daily intake of selenium should be
approximately 100 µg per day. This compound has a two-sided effect depending on its …