Generic antiepileptic drugs (AED) are significantly cheaper than brand name drugs, and
may reduce overall health care expenditures. Regulatory bodies in Europe and North …

Background. The common practice of switching between branded (reference) medications
and their corresponding generic products, between generic products, or even from a generic …

Objective To evaluate the frequency of reported antiseizure medication (ASM) supply
problems among patients with epilepsy (PWE) in Germany. Methods The Epi2020 study was …

Study Objective Generic drugs contain identical active ingredients as their corresponding
brand drugs and are pharmaceutically equivalent and bioequivalent, whereas authorized …

The objective was to develop and externally validate a population pharmacokinetic model of
levetiracetam in adult and elderly patients with epilepsy, and to perform dosing simulations …

The brand interchangeability of antiepileptic drugs (AEDs) is a topic of debate, especially
regarding their therapeutic equivalence. This study evaluates the efficacy and tolerability of …

Purpose Levetiracetam is one of the most widely used antiepileptic drugs, but the evidence
related to the safety of substitution from brand name to generic levetiracetam is scarce. The …

Objectives Generic antiepileptic drugs represent a measure to maximize cost saving.
Levetiracetam (LEV) is one of most commonly used and effective antiepileptic drugs. The …

Purpose The approach to the use of generic antiepileptic drugs has recently evolved from
major concern to general acceptance, but the evidence related specifically to the safety of …

Introduction The clinical, social, and economic burden of epilepsy is undeniable. Local
guidance on epilepsy management is limited and needed to address the both use of anti …