[HTML][HTML] A comprehensive account on recent progress in pharmacological activities of benzimidazole derivatives

SR Brishty, MJ Hossain, MU Khandaker… - Frontiers in …, 2021 - frontiersin.org
Nowadays, nitrogenous heterocyclic molecules have attracted a great deal of interest
among medicinal chemists. Among these potential heterocyclic drugs, benzimidazole …

Ethosomes as nanocarriers for the development of skin delivery formulations

AC Paiva-Santos, AL Silva, C Guerra, D Peixoto… - Pharmaceutical …, 2021 - Springer
The use of nanotechnology has been extensively explored for developing efficient drug
delivery systems towards topical and transdermal applications. Ethosomes constitute a …

[HTML][HTML] Recent applications of the multicomponent synthesis for bioactive pyrazole derivatives

D Becerra, R Abonia, JC Castillo - Molecules, 2022 - mdpi.com
Pyrazole and its derivatives are considered a privileged N-heterocycle with immense
therapeutic potential. Over the last few decades, the pot, atom, and step economy (PASE) …

[HTML][HTML] Structure–activity relationship analysis of benzimidazoles as emerging anti-inflammatory agents: An overview

R Veerasamy, A Roy, R Karunakaran, H Rajak - Pharmaceuticals, 2021 - mdpi.com
A significant number of the anti-inflammatory drugs currently in use are becoming obsolete.
These are exceptionally hazardous for long-term use because of their possible unfavourable …

Insights into the structure activity relationship of nitrogen-containing heterocyclics for the development of antidepressant compounds: An updated review

K Singh, R Pal, SA Khan, B Kumar, MJ Akhtar - Journal of Molecular …, 2021 - Elsevier
Abstract According to the World Health Organization (WHO), depression is a common
mental disorder and includes complex interaction between social and psychological …

A facile approach synthesis of benzoylaryl benzimidazole as potential α-amylase and α-glucosidase inhibitor with antioxidant activity

LM Aroua, HR Almuhaylan, FM Alminderej… - Bioorganic …, 2021 - Elsevier
Synthetic routes to a series of benzoylarylbenzimidazol 3a-h have been derived from 3, 4-
diaminobenzophenone and an appropriate arylaldehyde in the presence of ammonium …

Design, synthesis and molecular docking of new pyrazole-thiazolidinones as potent anti-inflammatory and analgesic agents with TNF-α inhibitory activity

SS Abd El-Karim, HS Mohamed, MF Abdelhameed… - Bioorganic …, 2021 - Elsevier
A new set of derivatives bearing pyrazole-methylenehydrazono-thiazolidinone scaffold 4–23
was designed, synthesized and confirmed by different spectroscopic means and elemental …

[HTML][HTML] Synthesis of antimicrobial benzimidazole–pyrazole compounds and their biological activities

M Marinescu - Antibiotics, 2021 - mdpi.com
The synthesis of new compounds with antimicrobial and antiviral properties is a central
objective today in the context of the COVID-19 pandemic. Benzimidazole and pyrazole …

[HTML][HTML] Thiophene-based compounds with potential anti-inflammatory activity

RMD da Cruz, FJB Mendonça-Junior, NB de Mélo… - Pharmaceuticals, 2021 - mdpi.com
Rheumatoid arthritis, arthrosis and gout, among other chronic inflammatory diseases are
public health problems and represent major therapeutic challenges. Non-steroidal anti …

[HTML][HTML] Foliar Applications of Bacillus subtilis HA1 Culture Filtrate Enhance Tomato Growth and Induce Systemic Resistance against Tobacco mosaic virus Infection

H El-Gendi, AA Al-Askar, L Király, MA Samy… - Horticulturae, 2022 - mdpi.com
The application of microbial products as natural biocontrol agents for inducing systemic
resistance against plant viral infections represents a promising strategy for sustainable and …