Apoptosis and its therapeutic implications in neurodegenerative diseases
NS Erekat - Clinical Anatomy, 2022 - Wiley Online Library
Neurodegenerative disorders are characterized by progressive loss of particular populations
of neurons. Apoptosis has been implicated in the pathogenesis of neurodegenerative …
of neurons. Apoptosis has been implicated in the pathogenesis of neurodegenerative …
Relationships between stress granules, oxidative stress, and neurodegenerative diseases
Cytoplasmic stress granules (SGs) are critical for facilitating stress responses and for
preventing the accumulation of misfolded proteins. SGs, however, have been linked to the …
preventing the accumulation of misfolded proteins. SGs, however, have been linked to the …
AP39, a novel mitochondria-targeted hydrogen sulfide donor, stimulates cellular bioenergetics, exerts cytoprotective effects and protects against the loss of …
B Szczesny, K Módis, K Yanagi, C Coletta… - Nitric oxide, 2014 - Elsevier
The purpose of the current study was to investigate the effect of the recently synthesized
mitochondrially-targeted H 2 S donor, AP39 [(10-oxo-10-(4-(3-thioxo-3H-1, 2-dithiol-5yl) …
mitochondrially-targeted H 2 S donor, AP39 [(10-oxo-10-(4-(3-thioxo-3H-1, 2-dithiol-5yl) …
H2S‐Releasing Versatile Montmorillonite Nanoformulation Trilogically Renovates the Gut Microenvironment for Inflammatory Bowel Disease Modulation
T Jin, H Lu, Q Zhou, D Chen, Y Zeng, J Shi… - Advanced …, 2024 - Wiley Online Library
Abnormal activation of the intestinal mucosal immune system, resulting from damage to the
intestinal mucosal barrier and extensive invasion by pathogens, contributes to the …
intestinal mucosal barrier and extensive invasion by pathogens, contributes to the …
The signaling mechanisms of hippocampal endoplasmic reticulum stress affecting neuronal plasticity-related protein levels in high fat diet-induced obese rats and the …
M Cai, H Wang, J Li, YL Zhang, L Xin, F Li… - Brain, behavior, and …, 2016 - Elsevier
High fat diet (HFD)-induced obesity has been shown to reduce the levels of neuronal
plasticity-related proteins, specifically brain-derived neurotrophic factor (BDNF) and …
plasticity-related proteins, specifically brain-derived neurotrophic factor (BDNF) and …
Stress granule: a promising target for cancer treatment
X Gao, L Jiang, Y Gong, X Chen, M Ying… - British journal of …, 2019 - Wiley Online Library
Stress granules (SGs) are primarily composed of mRNAs that stall at translation initiation
and usually appear in the cytoplasm under unusual physiological or pathological conditions …
and usually appear in the cytoplasm under unusual physiological or pathological conditions …
[HTML][HTML] Effect of alcohol on the central nervous system to develop neurological disorder: pathophysiological and lifestyle modulation can be potential therapeutic …
Z Pervin, JM Stephen - AIMS neuroscience, 2021 - ncbi.nlm.nih.gov
The central nervous system (CNS) is the major target for adverse effects of alcohol and
extensively promotes the development of a significant number of neurological diseases such …
extensively promotes the development of a significant number of neurological diseases such …
PGC-1α sparks the fire of neuroprotection against neurodegenerative disorders
J Lv, S Jiang, Z Yang, W Hu, Z Wang, T Li… - Ageing research reviews, 2018 - Elsevier
Recently, growing evidence has demonstrated that peroxisome proliferator activated
receptor γ (PPARγ) coactivator-1α (PGC-1α) is a superior transcriptional regulator that acts …
receptor γ (PPARγ) coactivator-1α (PGC-1α) is a superior transcriptional regulator that acts …
Oxidative stress as a therapeutic target in amyotrophic lateral sclerosis: Opportunities and limitations
HR Park, EJ Yang - Diagnostics, 2021 - mdpi.com
Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND) and Lou
Gehrig's disease, is characterized by a loss of the lower motor neurons in the spinal cord …
Gehrig's disease, is characterized by a loss of the lower motor neurons in the spinal cord …
Protective roles of Amanita caesarea polysaccharides against Alzheimer's disease via Nrf2 pathway
Z Li, X Chen, Y Zhang, X Liu, C Wang, L Teng… - International journal of …, 2019 - Elsevier
This study explores the neuro-protective effects of Amanita caesarea polysaccharides
(ACPS), obtained by 80% alcohol precipitation of water extract and purified using a DEAE …
(ACPS), obtained by 80% alcohol precipitation of water extract and purified using a DEAE …