Chitosan and its derivatives for application in mucoadhesive drug delivery systems

TM M. Ways, WM Lau, VV Khutoryanskiy - Polymers, 2018 - mdpi.com
Mucoadhesive drug delivery systems are desirable as they can increase the residence time
of drugs at the site of absorption/action, provide sustained drug release and minimize the …

[HTML][HTML] Impact of chitosan composites and chitosan nanoparticle composites on various drug delivery systems: A review

M Abd Elgadir, MS Uddin, S Ferdosh, A Adam… - Journal of food and drug …, 2015 - Elsevier
Chitosan is a promising biopolymer for drug delivery systems. Because of its beneficial
properties, chitosan is widely used in biomedical and pharmaceutical fields. In this review …

Chitosan-based drug delivery systems

A Bernkop-Schnürch, S Dünnhaupt - European journal of pharmaceutics …, 2012 - Elsevier
Within the past 20years, a considerable amount of work has been published on chitosan
and its potential use in drug delivery systems. In contrast to all other polysaccharides having …

Potential of insulin nanoparticle formulations for oral delivery and diabetes treatment

CY Wong, H Al-Salami, CR Dass - Journal of controlled release, 2017 - Elsevier
Nanoparticles have demonstrated significant advancements in potential oral delivery of
insulin. In this publication, we review the current status of polymeric, inorganic and solid-lipid …

Recent advances in chitosan-based nanoparticles for oral delivery of macromolecules

MC Chen, FL Mi, ZX Liao, CW Hsiao, K Sonaje… - Advanced drug delivery …, 2013 - Elsevier
Chitosan (CS), a cationic polysaccharide, is widely regarded as a safe and efficient intestinal
absorption enhancer of therapeutic macromolecules, owing to its inherent mucoadhesive …

Mucoadhesive and thermogelling systems for vaginal drug delivery

CM Caramella, S Rossi, F Ferrari, MC Bonferoni… - Advanced drug delivery …, 2015 - Elsevier
This review focuses on two formulation approaches, mucoadhesion and thermogelling,
intended for prolonging residence time on vaginal mucosa of medical devices or drug …

Chitosan nanoparticle-based system: A new insight into the promising controlled release system for lung cancer treatment

C Yee Kuen, MJ Masarudin - Molecules, 2022 - mdpi.com
Lung cancer has been recognized as one of the most often diagnosed and perhaps most
lethal cancer diseases worldwide. Conventional chemotherapy for lung cancer-related …

A focus on mucoadhesive polymers and their application in buccal dosage forms

E Russo, F Selmin, S Baldassari, CGM Gennari… - Journal of drug delivery …, 2016 - Elsevier
Mucosa of the buccal cavity is considered a convenient and easily accessible site for the
administration of drugs intended for both local and systemic delivery. Aiming to optimize the …

Recent trends in design and evaluation of chitosan-based colon targeted drug delivery systems: Update 2020

M Kurakula, S Gorityala, K Moharir - Journal of Drug Delivery Science and …, 2021 - Elsevier
Colon-targeted drug delivery systems is an active area of research that is designed to
selectively release the drug in the colonic environment to enhance the oral delivery of active …

PEGylated chitosan derivatives: Synthesis, characterizations and pharmaceutical applications

L Casettari, D Vllasaliu, E Castagnino, S Stolnik… - Progress in Polymer …, 2012 - Elsevier
This review sets out to describe and discuss the synthetic approaches and the fields of
application of PEGylated chitosan copolymers especially for medical use. The PEGylation of …