The neuroprotective potential of phytochemicals in traumatic brain injury: mechanistic insights and pharmacological implications
Traumatic brain injury (TBI) leads to brain damage, comprising both immediate primary
damage and a subsequent cascade of secondary injury mechanisms. The primary injury …
damage and a subsequent cascade of secondary injury mechanisms. The primary injury …
Potential therapeutic targets for trauma management
Z Li, O Qiao, Y Wang, N Li, Y Gong - Trends in Pharmacological Sciences, 2023 - cell.com
Despite advances in medical treatments for severe trauma, it remains a critical condition
associated with high mortality. During trauma, the release of endogenous damage …
associated with high mortality. During trauma, the release of endogenous damage …
The emerging role of mtDNA release in sepsis: Current evidence and potential therapeutic targets
Q Hong, S Zhu, Y Yu, Y Ren, L Jin… - Journal of Cellular …, 2024 - Wiley Online Library
Sepsis is a systemic inflammatory reaction caused by infection, and severe sepsis can
develop into septic shock, eventually leading to multiorgan dysfunction and even death. In …
develop into septic shock, eventually leading to multiorgan dysfunction and even death. In …
Mitochondrial dysfunction in inflammation and autoimmunity
J Staal, LP Blanco, A Perl - Frontiers in Immunology, 2023 - frontiersin.org
Mitochondria are the remnants of the ancient endosymbiont bacteria that together with a cell
related to the asgard archaea formed the original ur-eukaryote (1). Mitochondria are …
related to the asgard archaea formed the original ur-eukaryote (1). Mitochondria are …
Unveiling the role of mtDNA in Liver-Kidney Crosstalk: Insights from trichloroethylene hypersensitivity syndrome
X Zuo, L Gao, X Peng, L Dong, M Huang, T Hu… - International …, 2024 - Elsevier
In specific pathological conditions, addressing liver injury may yield favorable effects on
renal function through the phenomenon of liver-kidney crosstalk. Mitochondrial DNA …
renal function through the phenomenon of liver-kidney crosstalk. Mitochondrial DNA …
Mesenchymal Stem Cells Reduce the Extracellular Mitochondrial DNA-Mediated TLR9 Activation in Neonatal Hyperoxia-Induced Lung Injury
Mitochondrial DNA (mtDNA) released from dead or injured cells can activate inflammation,
and mesenchymal stem cell (MSC) transplantation can reduce inflammation and injury …
and mesenchymal stem cell (MSC) transplantation can reduce inflammation and injury …
[HTML][HTML] Th1/Th2 cytokines in early peripheral blood of patients with multiple injuries and its predictive value for SIRS: A bioinformatic analysis
S Chen, L Wang, R Zhu, J Yu - SLAS technology, 2024 - Elsevier
This study aims to evaluate the changes in helper T lymphocyte (Th) 1/Th2 factor levels in
peripheral blood of patients with severe multiple injuries and their prognostic value for …
peripheral blood of patients with severe multiple injuries and their prognostic value for …
Prevalencia y factores asociados a injuria cardiaca en trauma no cardíaco moderado a severo
LR Alva Lazaro de Reichelt - 2024 - repositorio.upao.edu.pe
Determinar si en pacientes con trauma moderado y grave, la prevalencia de injuria cardiaca
no traumática es superior al 10% e identificar sus factores asociados. Métodos: Se realizó …
no traumática es superior al 10% e identificar sus factores asociados. Métodos: Se realizó …