Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the
death of both upper and lower motor neurons (MNs) in the brain, brainstem and spinal cord …

Amyotrophic lateral sclerosis (ALS) is a fatal adult‐onset disease primarily characterized by
upper and lower motor neuron degeneration, muscle wasting and paralysis. It is increasingly …

Despite considerable unmet medical needs, effective pharmacological treatments that
promote functional recovery after spinal cord injury remain limited. Although multiple …

The onset of amyotrophic lateral sclerosis (ALS) is conventionally considered as
commencing with the recognition of clinical symptoms. We propose that, in common with …

Amyotrophic lateral sclerosis (ALS) is a fatal paralytic disorder caused by dysfunction and
degeneration of motor neurons. Multiple disease-causing mutations, including in the genes …

Toxic proteinaceous deposits and alterations in excitability and activity levels characterize
vulnerable neuronal populations in neurodegenerative diseases. Using in vivo two-photon …

In the motor system there is a complex interplay between cortical structures and spinal cord
lower motor neurons (LMN). In this system both inhibitory and excitatory neurons have …

Spinal muscular atrophy (SMA) and amyotrophic lateral sclerosis (ALS) are severe nervous
system diseases characterized by the degeneration of lower motor neurons. They share a …

Due to its extraordinary features such as large surface area, high electrical conductivity,
chemical stability and mechanical properties, graphene attracts great interest in various …

The complex neuronal networks of the spinal cord coordinate a wide variety of motor
functions, including walking, running, and voluntary and involuntary movements. This is …