Cathelicidins are short cationic peptides that are part of the innate immune system. At first,
these peptides were studied mostly for their direct antimicrobial killing capacity, but …

Host-defense peptides (HDPs) are vital components of innate immunity in all vertebrates.
While their antibacterial activity toward bacterial cells was the original focus for research …

Sight depends on the passage of light through the transparent cornea and being focused on
the fovea. Its exposed position renders it vulnerable to microbial infection. The cornea has …

Despite the availability of vaccines, Streptococcus pneumoniae (pneumococcus) remains a
serious cause of infections in the elderly. The efficacy of anti-pneumococcal vaccines …

Abstract Background Interleukin-33 (IL-33) is increasingly being recognized as a key
immunomodulatory cytokine in many neurological diseases. Methods In the present study …

Bacterial meningitis is, despite progress in research and the development of new treatment
strategies, still a cause of severe neuronal sequelae. The brain is protected from penetrating …

Antimicrobial peptides are key components of the innate immune system. They act as broad-
spectrum antimicrobial agents against Gram-positive and− negative bacteria, viruses, and …

Cathelicidin‐related antimicrobial peptide (CRAMP) is an effector molecule of the innate
immune system with direct antimicrobial and immunomodulatory activities; however, its role …

Background Bacterial meningitis is still a cause of severe neurological disability. The brain is
protected from penetrating pathogens by the blood-brain barrier and the innate immune …

This study examines the pharmacodynamics of antimicrobials that are used to treat
Salmonella with each other and with key components of the innate immune system …