Cellular senescence in skin‐related research: targeted signaling pathways and naturally occurring therapeutic agents
A Dańczak‐Pazdrowska, J Gornowicz‐Porowska… - Aging …, 2023 - Wiley Online Library
Despite the growing interest by researchers into cellular senescence, a hallmark of cellular
aging, its role in human skin remains equivocal. The skin is the largest and most accessible …
aging, its role in human skin remains equivocal. The skin is the largest and most accessible …
Diversity of fibroblasts and their roles in wound healing
D Jiang, R Guo, HG Machens… - Cold Spring Harbor …, 2023 - cshperspectives.cshlp.org
Wound healing disorders are a societal, clinical, and healthcare burden and understanding
and treating them is a major challenge. A particularly important cell type in the wound …
and treating them is a major challenge. A particularly important cell type in the wound …
[HTML][HTML] Hair shaft miniaturization causes stem cell depletion through mechanosensory signals mediated by a Piezo1-calcium-TNF-α axis
Y Xie, D Chen, K Jiang, L Song, N Qian, Y Du, Y Yang… - Cell Stem Cell, 2022 - cell.com
In aging, androgenic alopecia, and genetic hypotrichosis disorders, hair shaft miniaturization
is often associated with hair follicle stem cell (HFSC) loss. However, the mechanism causing …
is often associated with hair follicle stem cell (HFSC) loss. However, the mechanism causing …
The dermal sheath: An emerging component of the hair follicle stem cell niche
PA Martino, N Heitman, M Rendl - Experimental dermatology, 2021 - Wiley Online Library
Hair follicles cyclically regenerate throughout adult mammalian life, owing to a resident
population of epithelial hair follicle stem cells. Stem cell (SC) activity drives bouts of follicle …
population of epithelial hair follicle stem cells. Stem cell (SC) activity drives bouts of follicle …
Immune modulation of hair follicle regeneration
The mammalian hair follicle undergoes repeated bouts of regeneration orchestrated by a
variety of hair follicle stem cells. The last decade has witnessed the emergence of the …
variety of hair follicle stem cells. The last decade has witnessed the emergence of the …
Single‐cell transcriptomic analysis of small and large wounds reveals the distinct spatial organization of regenerative fibroblasts
Wound‐induced hair follicle neogenesis (WIHN) has been an important model to study hair
follicle regeneration during wound repair. However, the cellular and molecular components …
follicle regeneration during wound repair. However, the cellular and molecular components …
[HTML][HTML] Microenvironmental reprogramming of human dermal papilla cells for hair follicle tissue engineering
Z Liu, J Huang, D Kang, Y Zhou, L Du, Q Qu, J Wang… - Acta Biomaterialia, 2023 - Elsevier
The restoration of hair-inductive potential in human dermal papilla cells (hDPCs) is a
tremendous challenge for hair regeneration. Much of the research thus far has indicated that …
tremendous challenge for hair regeneration. Much of the research thus far has indicated that …
Single-cell RNA profiling of human skin reveals age-related loss of dermal sheath cells and their contribution to a juvenile phenotype
JMD Ahlers, C Falckenhayn, N Holzscheck… - Frontiers in …, 2022 - frontiersin.org
The dermal sheath (DS) is a population of mesenchyme-derived skin cells with emerging
importance for skin homeostasis. The DS includes hair follicle dermal stem cells, which …
importance for skin homeostasis. The DS includes hair follicle dermal stem cells, which …
Collagen Hydrolysate from the Scales of Mozambique Tilapia (Oreochromis mossambicus) Improve Hair and Skin Health by Alleviating Oxidative Stress and …
SB Hwang, HJ Park, BH Lee - Marine Drugs, 2023 - mdpi.com
Fish-derived collagen hydrolysate (CH) has shown promise in improving hair and skin
health. Therefore, this study sought to comprehensively assess the effects of CH extracted …
health. Therefore, this study sought to comprehensively assess the effects of CH extracted …
A story of fibers and stress: Matrix‐embedded signals for fibroblast activation in the skin
Our skin is continuously exposed to mechanical challenge, including shear, stretch, and
compression. The extracellular matrix of the dermis is perfectly suited to resist these …
compression. The extracellular matrix of the dermis is perfectly suited to resist these …