Over 50% of the global population suffers from hair loss. The mixed results in the treatment
of hair loss reveal the limitations of conventional commercial topical drugs. One the one …

The skin is the largest organ of the human body, composed of a diverse range of cell types,
non-cellular components, and an extracellular matrix. With aging, molecules that are part of …

Background: Androgenic alopecia (AGA) is characterized by progressive hair follicle
miniaturization, and novel treatments are needed to intervene in the miniaturization process …

Mesenchymal stem cells (MSCs) are known for their self-renewal and multi-lineage
differentiation potential, with these cells often being evaluated in the regulation and …

The health of hair is directly related to people's health and appearance. Hair has key
physiological functions, including skin protection and temperature regulation. Hair follicle …

The mesenchymal components of the hair follicle—the dermal papilla (DP) and dermal
sheath (DS)—are maintained by hair follicle dermal stem cells, but the position of this stem …

Androgenetic alopecia (AGA) affects more than half of the adult population worldwide and is
primarily caused by the binding of dihydrotestosterone (DHT) to androgen receptors (AR) …

Osteoarthritis affects 15% of people over 65 years of age. It is characterized by articular
cartilage degradation and inflammation, leading to joint pain and disability. Osteoarthritis is …

In mammalian testis, contractile peritubular myoid cells (PMCs) regulate the transport of
sperm and luminal fluid, while secreting growth factors and extracellular matrix proteins to …

Interactions between epithelial and mesenchymal cells influence hair follicles (HFs) during
embryonic development and skin regeneration following injury. Exchanging soluble …