Our understanding of the functions of the IL-1 superfamily cytokine and damage-associated
molecular pattern IL-33 continues to evolve with our understanding of homeostasis and …

Abstract Interleukin-33 (IL-33)—a member of the IL-1 family—was originally described as an
inducer of type 2 immune responses, activating T helper 2 (TH2) cells and mast cells. Now …

Il1rl1 (also known as ST2) is a member of the IL-1 superfamily, and its only known ligand is
IL-33. ST2 exists in two forms as splice variants: a soluble form (sST2), which acts as a …

Interleukin-33 (IL-33) is a nuclear-associated cytokine of the IL-1 family originally described
as a potent inducer of allergic type 2 immunity. IL-33 signals via the receptor ST2, which is …

Normal repair of skeletal muscle requires local expansion of a special population of Foxp3+
CD4+ regulatory T (Treg) cells. Such cells failed to accumulate in acutely injured muscle of …

Skeletal muscle is composed of a large and heterogeneous assortment of cell populations
that interact with each other to maintain muscle homeostasis and orchestrate regeneration …

Abstract Interleukin 33 (IL-33) is a member of the IL-1 family of cytokines with a growing
number of target cells and a plethora of biological functions. Although it has commonalities …

Abstract Interleukin-33 (IL-33), a member of the IL-1 family, and its cognate receptor,
Interleukin-1 receptor like-1 (IL-1RL1 or ST2), are susceptibility genes for childhood asthma …

Summary Interleukin (IL)‐33 is a key cytokine involved in type 2 immunity and allergic
airway diseases. Abundantly expressed in lung epithelial cells, IL‐33 plays critical roles in …

Interleukin-33 (IL-33) is a pleiotropic cytokine that can promote type 2 inflammation but also
drives immunoregulation through Foxp3+ Treg expansion. How IL-33 is exported from cells …