Obesity is a complex, chronic disease and global public health challenge. Characterized by
excessive fat accumulation in the body, obesity sharply increases the risk of several …

Obesity is a complex multifactorial disorder with genetic and environmental factors. There is
an increase in the worldwide prevalence of obesity in both developed and developing …

The ability of the body to maintain homeostasis requires constant communication between
the brain and peripheral tissues. Different organs produce signals, often in the form of …

Overnutrition is a risk factor for various human diseases, including neurodegenerative
diseases, metabolic disorders, and cancers. Therefore, targeting overnutrition represents a …

Schizophrenia (SCZ) is a serious mental illness that affects 1% of people worldwide. SCZ is
associated with a higher risk of developing metabolic disorders such as obesity …

Currently available data on the involvement of neuropeptide Y (NPY), peptide YY (PYY), and
pancreatic polypeptide (PP) and their receptors (YRs) in cancer are updated. The structure …

As a multi-potency cytokine, leptin not only plays a crucial role in controlling weight and
energy homeostasis but also participates in the metabolic balance in the human body …

Kdm6a is an X chromosome-linked H3K27me2/3 demethylase that promotes chromatin
accessibility and gene transcription and is critical for tissue/cell-specific differentiation …

Consumption of a high calorie diet with irregular eating and sedentary behavior habits is
typical of the current suboptimal lifestyle, contributing to the development of metabolic …

Polycystic ovary syndrome (PCOS) is a complex endocrine disease that can cause female
infertility and bring economic burden to families and to society. The clinical and/or …