Emulating a trial of joint dynamic strategies: an application to monitoring and treatment of HIV‐positive individuals

EC Caniglia, JM Robins, LE Cain, C Sabin… - Statistics in …, 2019 - Wiley Online Library
Decisions about when to start or switch a therapy often depend on the frequency with which
individuals are monitored or tested. For example, the optimal time to switch antiretroviral …

Ai-boosted crispr-cas13a and total internal reflection fluorescence microscopy system for sars-cov-2 detection

L Zhang, Z Lei, C Xiao, Z Du, C Jiang, X Yuan… - Frontiers in …, 2022 - frontiersin.org
Integrating artificial intelligence (AI) with SARS-CoV-2 diagnostics can help in the timely
execution of pandemic control and monitoring plans. To improve the efficiency of the …

Monitoring of kidney function in HIV‐positive patients

JC Yombi, R Jones, A Pozniak, JM Hougardy… - HIV …, 2015 - Wiley Online Library
HIV‐positive patients are at increased risk of developing chronic kidney disease. Although
guidelines recommend regular monitoring of renal function in individuals living with HIV, the …

Association between engagement in-care and mortality in HIV-positive persons

CA Sabin, A Howarth, S Jose, T Hill, V Apea, S Morris… - Aids, 2017 - journals.lww.com
Objective: To assess associations between engagement in-care and future mortality.
Design: UK-based observational cohort study. Methods: HIV-positive participants with more …

[HTML][HTML] When to monitor CD4 cell count and HIV RNA to reduce mortality and AIDS-defining illness in virologically suppressed HIV-positive persons on antiretroviral …

EC Caniglia, C Sabin, JM Robins… - JAIDS Journal of …, 2016 - journals.lww.com
Objective: To illustrate an approach to compare CD4 cell count and HIV-RNA monitoring
strategies in HIV-positive individuals on antiretroviral therapy (ART). Design: Prospective …

[HTML][HTML] Implementing HIV-1 genotypic resistance testing in antiretroviral therapy programs in Africa: needs, opportunities, and challenges

RJ Lessells, A Avalos, T de Oliveira - AIDS reviews, 2013 - ncbi.nlm.nih.gov
Tremendous progress has been made with the scale-up of antiretroviral therapy in Africa,
with an estimated seven million people now receiving antiretroviral therapy in the region …

Atazanavir exposure in utero and neurodevelopment in infants: a comparative safety study

EC Caniglia, K Patel, Y Huo, PL Williams… - Aids, 2016 - journals.lww.com
Objective: To evaluate the safety of in-utero exposure to atazanavir and neurodevelopment
in perinatally HIV-exposed but uninfected (PHEU) infants. Design: Prospective cohort study …

Total protein, albumin and low-molecular-weight protein excretion in HIV-positive patients

LJ Campbell, T Dew, R Salota, E Cheserem, L Hamzah… - BMC nephrology, 2012 - Springer
Background Chronic kidney disease is common in HIV positive patients and renal tubular
dysfunction has been reported in those receiving combination antiretroviral therapy (cART) …

Etravirine: a review of its use in the management of treatment-experienced patients with HIV-1 infection

JD Croxtall - Drugs, 2012 - Springer
Etravirine (Intelence®) is an orally administered next-generation non-nucleoside reverse
transcriptase inhibitor (NNRTI). It is approved for the treatment of HIV-1 infection in treatment …

HIV-1 tropism determination using a phenotypic Env recombinant viral assay highlights overestimation of CXCR4-usage by genotypic prediction algorithms for …

M Mulinge, M Lemaire, JY Servais, A Rybicki, D Struck… - PloS one, 2013 - journals.plos.org
Background Human Immunodeficiency virus type-1 (HIV) entry into target cells involves
binding of the viral envelope (Env) to CD4 and a coreceptor, mainly CCR5 or CXCR4. The …