Challenges for clinical development of vaccines for prevention of hospital-acquired bacterial infections
I Bekeredjian-Ding - Frontiers in immunology, 2020 - frontiersin.org
Increasing antibiotic resistance in bacteria causing endogenous infections has entailed a
need for innovative approaches to therapy and prophylaxis of these infections and raised a …
need for innovative approaches to therapy and prophylaxis of these infections and raised a …
Immune and Inflammatory Reponses to Staphylococcus aureus Skin Infections
Abstract Purpose of Review There have been recent advances in our understanding of
cutaneous immune responses to the important human skin pathogen, Staphylococcus …
cutaneous immune responses to the important human skin pathogen, Staphylococcus …
Whole-genome epidemiology, characterisation, and phylogenetic reconstruction of Staphylococcus aureus strains in a paediatric hospital
Background Staphylococcus aureus is an opportunistic pathogen and a leading cause of
nosocomial infections. It can acquire resistance to all the antibiotics that entered the clinics …
nosocomial infections. It can acquire resistance to all the antibiotics that entered the clinics …
Pharmacotherapeutic options for treating Staphylococcus aureus bacteremia
C Gudiol, G Cuervo, E Shaw, M Pujol… - Expert Opinion on …, 2017 - Taylor & Francis
Introduction: Case-fatality rates for Staphylococcus aureus bacteremia (SAB) remain
unacceptably high and have improved only modestly in recent decades. Treatment of SAB is …
unacceptably high and have improved only modestly in recent decades. Treatment of SAB is …
Staphylococcus aureus Toxins: From Their Pathogenic Roles to Anti-virulence Therapy Using Natural Products
MK Kim - Biotechnology and Bioprocess Engineering, 2019 - Springer
Staphylococcus aureus (S. aureus) produces a wide variety of toxins that cause various
diseases in humans. S. aureus toxins are divided into three categories;(i) superantigens …
diseases in humans. S. aureus toxins are divided into three categories;(i) superantigens …
Identification of biologic agents to neutralize the bicomponent leukocidins of Staphylococcus aureus
A key aspect underlying the severity of infections caused by Staphylococcus aureus is the
abundance of virulence factors that the pathogen uses to thwart critical components of the …
abundance of virulence factors that the pathogen uses to thwart critical components of the …
Antibiotic combined with epitope-specific monoclonal antibody cocktail protects mice against bacteremia and acute pneumonia from methicillin-resistant …
LL Duan, J Zhang, Z Chen, Q Gou, Q Xiong… - Journal of …, 2021 - Taylor & Francis
Purpose We previously reported that monoclonal antibody (mAb) cocktail improves survival
in Staphylococcus aureus infection. In this study, we used acute pneumonia model and …
in Staphylococcus aureus infection. In this study, we used acute pneumonia model and …
TPST2-mediated receptor tyrosine sulfation enhances leukocidin cytotoxicity and S. aureus infection
J He, X Yang, K Yang, H Xu, C Chen, J Wang… - Frontiers in …, 2023 - frontiersin.org
Background An essential fact underlying the severity of Staphylococcus aureus (S. aureus)
infection is the bicomponent leukocidins released by the pathogen to target and lyse host …
infection is the bicomponent leukocidins released by the pathogen to target and lyse host …
A computational investigation of potential plant-based bioactive compounds against drug-resistant Staphylococcus aureus of multiple target proteins
Drug-resistant Staphylococcus aureus (DRSA) poses a significant global health threat, like
bacteremia, endocarditis, skin, soft tissue, bone, and joint infections. Nowadays, the …
bacteremia, endocarditis, skin, soft tissue, bone, and joint infections. Nowadays, the …
Determining the immunological characteristics of a novel human monoclonal antibody developed against staphylococcal enterotoxin B
Y Liu, Z Song, S Ge, J Zhang, L Xu, F Yang… - Human Vaccines & …, 2020 - Taylor & Francis
Staphylococci are the main cause of nosocomial infections globally. The exotoxin
staphylococcal enterotoxin B (SEB) produced by methicillin-resistant Staphylococcus aureus …
staphylococcal enterotoxin B (SEB) produced by methicillin-resistant Staphylococcus aureus …