[HTML][HTML] The dominant role of forkhead box proteins in cancer

DH Bach, NP Long, TTT Luu, NH Anh… - International journal of …, 2018 - mdpi.com
Forkhead box (FOX) proteins are multifaceted transcription factors that are significantly
implicated in cancer, with various critical roles in biological processes. Herein, we provide …

[HTML][HTML] Transcription factors: The fulcrum between cell development and carcinogenesis

Z Islam, AM Ali, A Naik, M Eldaw, J Decock… - Frontiers in …, 2021 - frontiersin.org
Higher eukaryotic development is a complex and tightly regulated process, whereby
transcription factors (TFs) play a key role in controlling the gene regulatory networks …

FOX transcription factor family in hepatocellular carcinoma

Z Gong, J Yu, S Yang, PBS Lai, GG Chen - Biochimica et Biophysica Acta …, 2020 - Elsevier
The pathogenesis of hepatocellular carcinoma (HCC) is a multistep process, involving the
progressive accumulation of molecular alterations and transcriptomic alterations. The …

[HTML][HTML] Antisense lncRNA FOXF1-AS1 promotes migration and invasion of osteosarcoma cells through the FOXF1/MMP-2/-9 pathway

Z Kun-Peng, Z Chun-Lin… - International Journal of …, 2017 - ncbi.nlm.nih.gov
Osteosarcoma (OS) is the most common primary malignant bone cancer in children and
adolescents. Long non-coding RNAs (lncRNAs) have been shown to play significant role in …

FOXF1 promotes angiogenesis and accelerates bevacizumab resistance in colorectal cancer by transcriptionally activating VEGFA

S Wang, Z Xiao, Z Hong, H Jiao, S Zhu, Y Zhao, J Bi… - Cancer letters, 2018 - Elsevier
Abstract Forkhead box F1 (FOXF1) has been recently implicated in the progression and
metastasis of lung cancer and breast cancer. However, the biological functions and …

[HTML][HTML] FOXF1 induces epithelial-mesenchymal transition in colorectal cancer metastasis by transcriptionally activating SNAI1

S Wang, S Yan, S Zhu, Y Zhao, J Yan, Z Xiao, J Bi… - Neoplasia, 2018 - Elsevier
Abstract Forkhead Box F1 (FOXF1) has been recently implicated in cancer progression and
metastasis of lung cancer and breast cancer. However, the biological functions and …

[HTML][HTML] Loss of FOXF1 expression promotes human lung-resident mesenchymal stromal cell migration via ATX/LPA/LPA1 signaling axis

P Cao, NM Walker, RR Braeuer, S Mazzoni-Putman… - Scientific Reports, 2020 - nature.com
Abstract Forkhead box F1 (FOXF1) is a lung embryonic mesenchyme-associated
transcription factor that demonstrates persistent expression into adulthood in mesenchymal …

[HTML][HTML] Forkhead box F1 functions as a novel prognostic biomarker and induces caspase‑dependent apoptosis in bladder cancer

Y Hao, W He, H Wang, W Rui, F Sun… - Oncology …, 2023 - spandidos-publications.com
The downregulated expression of forkhead box F1 (FOXF1) has been found in many
malignant tumors but no research was done in bladder cancer (BC). The present study …

FOXF1 ameliorates angiotensin II-induced cardiac fibrosis in cardiac fibroblasts through inhibiting the TGF-β1/Smad3 signaling pathway

D Jin, F Han - Journal of Receptors and Signal Transduction, 2020 - Taylor & Francis
Cardiac fibrosis is a pathological feature common to a variety of heart diseases such as
myocardial infarction, arrhythmias, cardiomyopathies and heart failure. The molecular …

Diagnostic value of FOXF1 gene promoter-methylated DNA in the plasma samples of patients with colorectal cancer

Z Dastafkan, N Rezvani… - The International Journal …, 2023 - journals.sagepub.com
Background Epigenetic modifications such as DNA methylation in the CpG islands of genes
occur at a high rate. In this study, we measured the methylation level of the promoter region …