[HTML][HTML] Animal models of epilepsy: a phenotype-oriented review

Y Wang, P Wei, F Yan, Y Luo, G Zhao - Aging and disease, 2022 - ncbi.nlm.nih.gov
Epilepsy is a serious neurological disorder characterized by abnormal, recurrent, and
synchronous discharges in the brain. Long-term recurrent seizure attacks can cause serious …

Chronic electroencephalography in epilepsy with a responsive neurostimulation device: current status and future prospects

VR Rao - Expert Review of Medical Devices, 2021 - Taylor & Francis
Introduction Implanted neurostimulation devices are gaining traction as therapeutic options
for people with certain forms of drug-resistant focal epilepsy. Some of these devices enable …

Identification of different MRI atrophy progression trajectories in epilepsy by subtype and stage inference

F Xiao, L Caciagli, B Wandschneider, D Sone… - Brain, 2023 - academic.oup.com
Artificial intelligence (AI)-based tools are widely employed, but their use for diagnosis and
prognosis of neurological disorders is still evolving. Here we analyse a cross-sectional …

FAIR Genomes metadata schema promoting Next Generation Sequencing data reuse in Dutch healthcare and research

KJ van der Velde, G Singh, R Kaliyaperumal, XF Liao… - Scientific data, 2022 - nature.com
The genomes of thousands of individuals are profiled within Dutch healthcare and research
each year. However, this valuable genomic data, associated clinical data and consent are …

Artificial intelligence in epilepsy phenotyping

A Knight, T Gschwind, P Galer, GA Worrell, B Litt… - …, 2024 - Wiley Online Library
Artificial intelligence (AI) allows data analysis and integration at an unprecedented
granularity and scale. Here we review the technological advances, challenges, and future …

Deep learning approaches for seizure video analysis: A review

D Ahmedt-Aristizabal, MA Armin, Z Hayder… - Epilepsy & Behavior, 2024 - Elsevier
Seizure events can manifest as transient disruptions in the control of movements which may
be organized in distinct behavioral sequences, accompanied or not by other observable …

Integrating network neuroscience into epilepsy care: Progress, barriers, and next steps

N Sinha, GW Johnson, KA Davis… - Epilepsy …, 2022 - journals.sagepub.com
Drug resistant epilepsy is a disorder involving widespread brain network alterations.
Recently, many groups have reported neuroimaging and electrophysiology network analysis …

Modeling seizures in the Human Phenotype Ontology according to contemporary ILAE concepts makes big phenotypic data tractable

D Lewis‐Smith, PD Galer, G Balagura, H Kearney… - …, 2021 - Wiley Online Library
Objective The clinical features of epilepsy determine how it is defined, which in turn guides
management. Therefore, consideration of the fundamental clinical entities that comprise an …

Automated video analysis of emotion and dystonia in epileptic seizures

JC Hou, M Thonnat, F Bartolomei, A McGonigal - Epilepsy Research, 2022 - Elsevier
Objective To investigate the accuracy of deep learning methods applied to seizure video
data, in discriminating individual semiologic features of dystonia and emotion in epileptic …

Design, implementation, and inferential issues associated with clinical trials that rely on data in electronic medical records: a narrative review

A Leviton, T Loddenkemper - BMC Medical Research Methodology, 2023 - Springer
Real world evidence is now accepted by authorities charged with assessing the benefits and
harms of new therapies. Clinical trials based on real world evidence are much less …