[HTML][HTML] Protective role of melatonin and its metabolites in skin aging

G Bocheva, RM Slominski, Z Janjetovic, TK Kim… - International journal of …, 2022 - mdpi.com
The skin, being the largest organ in the human body, is exposed to the environment and
suffers from both intrinsic and extrinsic aging factors. The skin aging process is …

Melatonin as a mitochondria-targeted antioxidant: one of evolution's best ideas

RJ Reiter, S Rosales-Corral, DX Tan, MJ Jou… - Cellular and molecular …, 2017 - Springer
Melatonin is an ancient antioxidant. After its initial development in bacteria, it has been
retained throughout evolution such that it may be or may have been present in every species …

[HTML][HTML] Oxidative stress: Normal pregnancy versus preeclampsia

DI Chiarello, C Abad, D Rojas, F Toledo… - … et Biophysica Acta (BBA …, 2020 - Elsevier
The role of oxidative stress in the physiopathology of human pregnancy is of particular
interest. Pregnancy is well-known to increase the oxidative stress, mainly produced by a …

Mitochondria: central organelles for melatonin′ s antioxidant and anti-aging actions

RJ Reiter, DX Tan, S Rosales-Corral, A Galano… - Molecules, 2018 - mdpi.com
Melatonin, along with its metabolites, have long been known to significantly reduce the
oxidative stress burden of aging cells or cells exposed to toxins. Oxidative damage is a …

Melatonin, a full service anti-cancer agent: inhibition of initiation, progression and metastasis

RJ Reiter, SA Rosales-Corral, DX Tan… - International journal of …, 2017 - mdpi.com
There is highly credible evidence that melatonin mitigates cancer at the initiation,
progression and metastasis phases. In many cases, the molecular mechanisms …

Melatonin and its metabolites vs oxidative stress: From individual actions to collective protection

A Galano, RJ Reiter - Journal of Pineal Research, 2018 - Wiley Online Library
Oxidative stress (OS) represents a threat to the chemical integrity of biomolecules including
lipids, proteins, and DNA. The associated molecular damage frequently results in serious …

Melatonin enhances plant growth and abiotic stress tolerance in soybean plants

W Wei, QT Li, YN Chu, RJ Reiter, XM Yu… - Journal of …, 2015 - academic.oup.com
Melatonin is a well-known agent that plays multiple roles in animals. Its possible function in
plants is less clear. In the present study, we tested the effect of melatonin (N-acetyl-5 …

Melatonin: a versatile protector against oxidative DNA damage

A Galano, DX Tan, RJ Reiter - Molecules, 2018 - mdpi.com
Oxidative damage to DNA has important implications for human health and has been
identified as a key factor in the onset and development of numerous diseases. Thus, it is …

Comparative physiological, metabolomic, and transcriptomic analyses reveal mechanisms of improved abiotic stress resistance in bermudagrass [Cynodon dactylon …

H Shi, C Jiang, T Ye, DX Tan, RJ Reiter… - Journal of …, 2015 - academic.oup.com
Abstract Melatonin (N-acetyl-5-methoxytryptamine), a well-known animal hormone, is also
involved in plant development and abiotic stress responses. In this study, it is shown that …

Diabetic retinopathy pathogenesis and the ameliorating effects of melatonin; involvement of autophagy, inflammation and oxidative stress

E Dehdashtian, S Mehrzadi, B Yousefi… - Life sciences, 2018 - Elsevier
Diabetic retinopathy (DR), a microvascular complication of diabetes mellitus (DM), remains
as one of the major causes of vision loss worldwide. The release of pro-inflammatory …