Natural products and derivatives in renal, urothelial and testicular cancers: targeting signaling pathways and therapeutic potential

D Li, J Wang, Z Tuo, KH Yoo, Q Yu, A Miyamoto… - Phytomedicine, 2024 - Elsevier
Background: Natural products have demonstrated significant potential in cancer drug
discovery, particularly in renal cancer (RCa), urothelial carcinoma (UC), and testicular …

Approaches for boosting antitumor immunity in prostate cancer therapy: A comprehensive review on drugs, products, and nanoparticles

D Chen, Y Hu - Journal of Drug Delivery Science and Technology, 2023 - Elsevier
Prostate cancers are among the common malignancies in men. Despite the availability of
various treatment options, including chemotherapy, radiotherapy, and surgery, the prognosis …

Plant-derived vesicle-like nanoparticles: A new tool for inflammatory bowel disease and colitis-associated cancer treatment

X Fang, J Feng, X Zhu, D Feng, L Zheng - Molecular Therapy, 2024 - cell.com
Long-term use of conventional drugs to treat inflammatory bowel diseases (IBD) and colitis-
associated cancer (CAC) has an adverse impact on the human immune system and easily …

Exploiting the immune system in hepatic tumor targeting: unleashing the potential of drugs, natural products, and nanoparticles

CY Hsu, MA Mustafa, A Kumar, A Pramanik… - … -Research and Practice, 2024 - Elsevier
Hepatic tumors present a formidable challenge in cancer therapeutics, necessitating the
exploration of novel treatment strategies. In recent years, targeting the immune system has …

Nanocarriers for delivering nucleic acids and chemotherapeutic agents as combinational approach: Challenges, clinical progress, and unmet needs

M Rahman, O Afzal, SNMN Ullah… - Journal of Drug Delivery …, 2023 - Elsevier
Cancer is the second leading cause of death after heart disease. It forms clusters of
immature cells, spreads through metastasis, and invades normal tissue. Chemotherapeutic …

Targeting the oral tumor microenvironment by nanoparticles: A review of progresses

H Zhang, F Zhou, Q Yang, M Huang - Journal of Drug Delivery Science and …, 2023 - Elsevier
Oral tumors are a significant health concern, with a large number of side effects, remarkable
mortality, and limited treatment options. Targeting the tumor stroma, which has key impacts …

Self‐Assembled Fe‐Phenolic Acid Network Synergizes with Ferroptosis to Enhance Tumor Nanotherapy

Y Chen, X Yang, H Li, X Wu, W Wu, J Chen, A Wu… - Small, 2024 - Wiley Online Library
Natural polyphenolic compound rosmarinic acid (RA) has good antitumor activity. However,
the distinctive tumor microenvironment, characterized by low pH and elevated levels of …

[HTML][HTML] Dioscin inhibits non-small cell lung cancer cells and activates apoptosis by downregulation of Survivin

R Wang, X Li, Y Gan, J Liao, S Han, W Li… - Journal of …, 2024 - ncbi.nlm.nih.gov
Human malignancies exhibit elevated levels of survivin, and have been linked to poor
prognosis. Targeting survivin expression is a promising therapeutic strategy against cancer …

[HTML][HTML] Potential of melatonin to reverse epigenetic aberrations in oral cancer: new findings

E Gil-Martín, E Ramos, F López-Muñoz, J Egea… - EXCLI …, 2023 - ncbi.nlm.nih.gov
It is now an accepted principle that epigenetic alterations cause cellular dyshomeostasis
and functional changes, both of which are essential for the initiation and completion of the …

Targeting the breast tumor microenvironment by plant-derived products and their nanoformulations

H Zhang, Y Li - Journal of Drug Delivery Science and Technology, 2024 - Elsevier
Breast cancer is one of the considerable prevalent neoplasms worldwide. It is an intricate
disorder and various modalities alone or in combination have been suggested for the control …