TFOS DEWS II pain and sensation report

C Belmonte, JJ Nichols, SM Cox, JA Brock, CG Begley… - The ocular …, 2017 - Elsevier
Pain associated with mechanical, chemical, and thermal heat stimulation of the ocular
surface is mediated by trigeminal ganglion neurons, while cold thermoreceptors detect …

In vivo confocal microscopy of corneal nerves in health and disease

A Cruzat, Y Qazi, P Hamrah - The ocular surface, 2017 - Elsevier
In vivo confocal microscopy (IVCM) is becoming an indispensable tool for studying corneal
physiology and disease. Enabling the dissection of corneal architecture at a cellular level …

TFOS Lifestyle: Impact of lifestyle challenges on the ocular surface

A Galor, AC Britten-Jones, Y Feng, G Ferrari… - The ocular …, 2023 - Elsevier
Many factors in the domains of mental, physical, and social health have been associated
with various ocular surface diseases, with most of the focus centered on aspects of dry eye …

Neuropathic pain and dry eye

A Galor, HR Moein, C Lee, A Rodriguez, ER Felix… - The ocular …, 2018 - Elsevier
Dry eye is a common, multifactorial disease currently diagnosed by a combination of
symptoms and signs. Its epidemiology and clinical presentation have many similarities with …

Neuropathic corneal pain: approaches for management

G Dieckmann, S Goyal, P Hamrah - Ophthalmology, 2017 - Elsevier
Neuropathic pain is caused by a primary lesion or dysfunction of the nervous system and
can occur in the cornea. However, neuropathic corneal pain (NCP) is currently an ill-defined …

In vivo confocal microscopy detects bilateral changes of corneal immune cells and nerves in unilateral herpes zoster ophthalmicus

BM Cavalcanti, A Cruzat, A Sahin, D Pavan-Langston… - The ocular …, 2018 - Elsevier
Purpose To analyze bilateral corneal immune cell and nerve alterations in patients with
unilateral herpes zoster ophthalmicus (HZO) by laser in vivo confocal microscopy (IVCM) …

Efficacy of autologous serum tears for treatment of neuropathic corneal pain

S Aggarwal, C Colon, A Kheirkhah, P Hamrah - The ocular surface, 2019 - Elsevier
Objective Corneal nerve damage may result in neuropathic corneal pain (NCP). Autologous
serum tears (AST) have been shown to results in nerve regeneration and may help alleviate …

Coexistence of neuropathic corneal pain, corneal nerve abnormalities, depression, and low quality of life

A Leonardi, OM Feuerman, E Salami, D Lazzarini… - Eye, 2024 - nature.com
Purpose To evaluate the quality of life (QoL), mental health conditions and corneal
morphology in neuropathic corneal pain (NCP) subjects without a significant ocular surface …

[HTML][HTML] Visualization of microneuromas by using in vivo confocal microscopy: An objective biomarker for the diagnosis of neuropathic corneal pain?

HR Moein, A Akhlaq, G Dieckmann, A Abbouda… - The ocular …, 2020 - Elsevier
Purpose The diagnosis of neuropathic corneal pain (NCP) is challenging, as it is often
difficult to differentiate it from conventional dry eye disease (DED). In addition to eye pain …

Ocular surface pain: a narrative review

D Mehra, NK Cohen, A Galor - Ophthalmology and therapy, 2020 - Springer
Ocular surface pain is a frequent cause of visits to an eye care provider and has a
substantial impact on healthcare cost, yet a complete understanding of its causative factors …