Traumatic brain injury (TBI) results in both rapid and delayed brain damage. The speed,
complexity, and persistence of TBI present large obstacles to drug development. Preclinical …

Background Acute ischemic stroke (AIS) is a common cerebrovascular event associated with
high incidence, disability, and poor prognosis. Studies have shown that various cell types …

Glial cells expressing neuron‐glial antigen 2 (NG2), also known as oligodendrocyte
progenitor cells (OPCs), play a critical role in maintaining brain health. However, their ability …

Traumatic brain injury leads to a highly orchestrated immune-and glial cell response
partially responsible for long-lasting disability and the development of secondary …

Stroke is a major reason for persistent disability due to insufficient treatment strategies
beyond reperfusion, leading to oligodendrocyte death and axon demyelination, persistent …

á Oligodendrocyte progenitor cells (OPCs) represent a subtype of glia, giving rise to
oligodendrocytes, the myelin-forming cells in the central nervous system (CNS). While OPCs …

Aim Animals exhibit physiological changes designed to eliminate the perceived danger,
provoking similar symptoms of fever. However, a high‐grade fever indicates poor clinical …

In the central nervous system (CNS), cells of the oligodendroglial lineage represent a source
of regenerative potential, the extent of which currently is not entirely understood. The …

Reactive neuroglia critically shape the braińs response to ischemic stroke. However, their
phenotypic heterogeneity impedes a holistic understanding of the cellular composition and …

Axon degeneration and functional decline in myelin diseases are often attributed to loss of
myelin but their relation is not fully understood. Perturbed myelinating glia can instigate …