Associations of insulin and IGFBP-3 with lung cancer susceptibility in current smokers

GYF Ho, SL Zheng, M Cushman… - Journal of the …, 2016 - academic.oup.com
Background: The epidermal growth factor receptor (EGFR) signaling network is involved in
lung carcinogenesis. This study examined whether ligands that activate or suppress the …

In silico identification of potential key regulatory factors in smoking-induced lung cancer

SA El-Aarag, A Mahmoud, MH Hashem… - BMC medical …, 2017 - Springer
Background Lung cancer is a leading cause of cancer-related death worldwide and is the
most commonly diagnosed cancer. Like other cancers, it is a complex and highly …

The association between insulin resistance and cardiovascular disease risk: a community-based cross-sectional study among Taiwanese people aged over 50 years

MC Lu, WC Fang, WC Li, WC Yeh, YH Shieh… - International Journal of …, 2020 - mdpi.com
Background and Aims: Previous studies have implied that insulin resistance (IR) could
represent a major underlying abnormality leading to cardiovascular disease (CVD). The aim …

Physical activity and risk of lung cancer: a meta-analysis

S Zhong, T Ma, L Chen, W Chen, M Lv… - Clinical Journal of …, 2016 - journals.lww.com
Objective: Previous studies concerning the association between physical activity (PA) and
risk of lung cancer yielded mixed results. We investigated the association by performing a …

BMI changes and the risk of lung cancer in male never‐smokers: A prospective cohort study

Z Wu, S Xie, F Wang, S Chen, K Su, F Li, H Cui… - Cancer …, 2022 - Wiley Online Library
Background To investigate the association between the risk of lung cancer and short‐term
body mass index (BMI) changes in male never‐smokers of a large population‐based …

Cancer-disease associations: A visualization and animation through medical big data

U Iqbal, CK Hsu, PAA Nguyen, DL Clinciu, R Lu… - Computer methods and …, 2016 - Elsevier
Objective Cancer is the primary disease responsible for death and disability worldwide.
Currently, prevention and early detection represents the best hope for cure. Knowing the …

Diabetes and lung cancer among postmenopausal women

J Luo, R Chlebowski, J Wactawski-Wende… - Diabetes …, 2012 - Am Diabetes Assoc
OBJECTIVE Epidemiological evidence of diabetes as a lung cancer risk factor is limited and
conflicting. Therefore, we assessed associations among diabetes, diabetes therapy, and …

Glycemic status, insulin resistance, and mortality from lung cancer among individuals with and without diabetes

IY Cho, Y Chang, E Sung, B Park, JH Kang, H Shin… - Cancer & …, 2024 - Springer
Background The effects of glycemic status and insulin resistance on lung cancer remain
unclear. We investigated the associations between both glycemic status and insulin …

Triglyceride-glucose index is not associated with lung cancer risk: A prospective cohort study in the UK biobank

L Wang, S Si, J Li, Y Li, X Chen, F Xue, W Ren - Frontiers in Oncology, 2021 - frontiersin.org
Background The triglyceride-glucose (TyG) index is a practical substitute measure for insulin
resistance (IR). The relationship between IR and lung cancer has been examined in …

The association between METS-IR, an indirect index for insulin resistance, and lung cancer risk

G Wang, Z Zhu, Y Wang, Q Zhang, Y Sun… - European Journal of …, 2024 - academic.oup.com
Background Insulin resistance has been reported to increase the risk of breast, prostate and
colorectal cancer. However, the role of insulin resistance and its interaction with genetic risk …