Mechanical stress from haemodynamic perturbations or interventional manipulation of
epicardial coronary atherosclerotic plaques with inflammatory destabilization can release …

Bipolar disorder's core feature is the pathological disturbances in mood, often accompanied
by disrupted thinking and behavior. Its complex and heterogeneous etiology implies that a …

Heart failure is a systemic syndrome caused by multiple pathological factors. Current
treatments do not have satisfactory outcomes. Several basic studies have revealed the …

Reperfusion therapy has resulted in significant improvement in post-myocardial infarction
morbidity and mortality in over the last 4 decades. Nonetheless, it is well recognized that …

Background: Coronary artery bypass grafting (CABG) is a key and effective surgical
treatment modality for coronary artery disease. Unfortunately, ischemia-reperfusion injury …

Myocardial energy metabolism (MEM) is an important factor of myocardial injury.
Trimetazidine (TMZ) provides protection against myocardial ischemia/reperfusion injury. The …

Background/Aims: The local inflammatory response caused by coronary microembolization
(CME) is the primary cause of progressive cardiac dysfunction. The PDCD4/NF-κB/TNF-α …

Background Myocardial apoptosis is closely related to myocardial injury caused by coronary
microembolization (CME). Nuclear factor erythroid 2-like (Nrf2) has been taken into account …

Coronary microembolization (CME) is associated with cardiomyocyte apoptosis and cardiac
dysfunction. Puerarin confers protection against multiple cardiovascular diseases, but its …

Latest clinical research shows that trimetazidine therapy during the perioperative period
relieves endothelial dysfunction in patients with unstable angina induced by percutaneous …