Neutrophils in chronic inflammatory diseases

A Herrero-Cervera, O Soehnlein… - Cellular & molecular …, 2022 - nature.com
Chronic inflammation is a component of many disease conditions that affect a large group of
individuals worldwide. Chronic inflammation is characterized by persistent, low-grade …

The gut microbiome and inflammatory bowel diseases

Y Shan, M Lee, EB Chang - Annual review of medicine, 2022 - annualreviews.org
Inflammatory bowel diseases (IBD) arise from a convergence of genetic risk, environmental
factors, and gut microbiota, where each is necessary but not sufficient to cause disease …

Enterotoxigenic Bacteroides fragilis promotes intestinal inflammation and malignancy by inhibiting exosome-packaged miR-149-3p

Y Cao, Z Wang, Y Yan, L Ji, J He, B Xuan, C Shen… - Gastroenterology, 2021 - Elsevier
Background & Aims Enterotoxigenic Bacteroides fragilis (ETBF) is strongly associated with
the occurrence of inflammatory bowel disease (IBD), colitis-associated colorectal cancer …

Partners in crime: neutrophils and monocytes/macrophages in inflammation and disease

K Prame Kumar, AJ Nicholls, CHY Wong - Cell and tissue research, 2018 - Springer
Neutrophils are becoming recognized as highly versatile and sophisticated cells that display
de novo synthetic capacity and potentially prolonged lifespan. Emerging concepts such as …

Escherichia coli Pathobionts Associated with Inflammatory Bowel Disease

HC Mirsepasi-Lauridsen, BA Vallance… - Clinical microbiology …, 2019 - Am Soc Microbiol
Gut bacteria play a key role in initiating and maintaining the inflammatory process in the gut
tissues of inflammatory bowel disease (IBD) patients, by supplying antigens or other …

Revisiting inflammatory bowel disease: pathology, treatments, challenges and emerging therapeutics including drug leads from natural products

K Yeshi, R Ruscher, L Hunter, NL Daly… - Journal of clinical …, 2020 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic and life-long disease characterized by
gastrointestinal tract inflammation. It is caused by the interplay of the host's genetic …

Pglyrp-Regulated Gut Microflora Prevotella falsenii, Parabacteroides distasonis and Bacteroides eggerthii Enhance and Alistipes finegoldii Attenuates Colitis in …

R Dziarski, SY Park, DR Kashyap, SE Dowd, D Gupta - PloS one, 2016 - journals.plos.org
Dysbiosis is a hallmark of inflammatory bowel disease (IBD), but it is unclear which specific
intestinal bacteria predispose to and which protect from IBD and how they are regulated …

[HTML][HTML] A guide to histomorphological evaluation of intestinal inflammation in mouse models

U Erben, C Loddenkemper, K Doerfel… - … journal of clinical and …, 2014 - ncbi.nlm.nih.gov
Histomorphology remains a powerful routine evaluating intestinal inflammation in animal
models. Emphasizing the focus of a given animal study, histopathology can overstate …

Development of a gut-on-a-chip model for high throughput disease modeling and drug discovery

C Beaurivage, E Naumovska, YX Chang… - International journal of …, 2019 - mdpi.com
A common bottleneck in any drug development process is finding sufficiently accurate
models that capture key aspects of disease development and progression. Conventional …

Mechanisms and therapeutic effectiveness of lactobacilli

A Di Cerbo, B Palmieri, M Aponte… - Journal of clinical …, 2016 - jcp.bmj.com
The gut microbiome is not a silent ecosystem but exerts several physiological and
immunological functions. For many decades, lactobacilli have been used as an effective …