Efavirenz associated with cognitive disorders in otherwise asymptomatic HIV-infected patients
N Ciccarelli, M Fabbiani, S Di Giambenedetto, I Fanti… - Neurology, 2011 - AAN Enterprises
Background: Despite the availability of potent antiretroviral regimens (combination
antiretroviral therapy [cART]), HIV-associated neurocognitive disorders (HAND) are …
antiretroviral therapy [cART]), HIV-associated neurocognitive disorders (HAND) are …
HIV-1 infection and cognitive impairment in the cART era: a review
With the introduction of combination antiretroviral therapy AIDS dementia complex or HIV-
associated dementia, as it was termed later, largely disappeared in clinical practice …
associated dementia, as it was termed later, largely disappeared in clinical practice …
Breaking down the barrier: the effects of HIV-1 on the blood–brain barrier
M Strazza, V Pirrone, B Wigdahl, MR Nonnemacher - Brain research, 2011 - Elsevier
Human immunodeficiency virus type 1 (HIV-1) primarily infects CD4+ T cells and cells of the
monocyte–macrophage lineage, resulting in immunodeficiency in an infected patient. Along …
monocyte–macrophage lineage, resulting in immunodeficiency in an infected patient. Along …
Assessment, diagnosis, and treatment of HIV-associated neurocognitive disorder: a consensus report of the mind exchange program
Mind Exchange Working Group… - Clinical Infectious …, 2013 - academic.oup.com
Many practical clinical questions regarding the management of human immunodeficiency
virus (HIV)–associated neurocognitive disorder (HAND) remain unanswered. We sought to …
virus (HIV)–associated neurocognitive disorder (HAND) remain unanswered. We sought to …
Monocyte maturation, HIV susceptibility, and transmigration across the blood brain barrier are critical in HIV neuropathogenesis
DW Williams, EA Eugenin, TM Calderon… - Journal of leukocyte …, 2012 - academic.oup.com
ABSTRACT HIV continues to be a global health crisis with more than 34 million people
infected worldwide (UNAIDS: Report on the Global AIDS Epidemic 2010, Geneva, World …
infected worldwide (UNAIDS: Report on the Global AIDS Epidemic 2010, Geneva, World …
Effects of central nervous system antiretroviral penetration on cognitive functioning in the ALLRT cohort
M Smurzynski, K Wu, S Letendre, K Robertson… - Aids, 2011 - journals.lww.com
Objective: Differences in antiretroviral distribution into the central nervous system (CNS) may
impact neurocognitive status. We assessed the relationship between estimates of …
impact neurocognitive status. We assessed the relationship between estimates of …
[PDF][PDF] BHIVA guidelines on antiretroviral treatment for adults living with HIV-1 2022
L Waters, A Winston, I Reeves, M Boffito… - HIV …, 2022 - discovery.ucl.ac.uk
The overall purpose of these guidelines is to provide guidance on best clinical practice for
antiretroviral therapy (ART) and management of adults living with human immunodeficiency …
antiretroviral therapy (ART) and management of adults living with human immunodeficiency …
Could antiretroviral neurotoxicity play a role in the pathogenesis of cognitive impairment in treated HIV disease?
J Underwood, KR Robertson, A Winston - Aids, 2015 - journals.lww.com
Whilst effective antiretroviral therapy is protective against the more severe forms of HIV-
associated brain disease, there remains a large burden of clinically symptomatic cognitive …
associated brain disease, there remains a large burden of clinically symptomatic cognitive …
[HTML][HTML] Biomarker evidence of axonal injury in neuroasymptomatic HIV-1 patients
J Jessen Krut, T Mellberg, RW Price, L Hagberg… - PloS one, 2014 - journals.plos.org
Background Prevalence of neurocognitive impairment in HIV-1 infected patients is reported
to be high. Whether this is a result of active HIV-related neurodegeneration is unclear. We …
to be high. Whether this is a result of active HIV-related neurodegeneration is unclear. We …
Prevalence of non-confounded HIV-associated neurocognitive impairment in the context of plasma HIV RNA suppression
LA Cysique, BJ Brew - Journal of neurovirology, 2011 - Springer
HIV-associated neurocognitive disorder is known to occur in the context of successful
combination antiretroviral therapy (cART; plasma HIV RNA< 50 copies/ml). Here, we newly …
combination antiretroviral therapy (cART; plasma HIV RNA< 50 copies/ml). Here, we newly …