Normative data and validation of a regression based summary score for assessing meaningful neuropsychological change
LA Cysique, D Franklin Jr, I Abramson… - Journal of clinical and …, 2011 - Taylor & Francis
Reliable detection and quantification of longitudinal cognitive change are of considerable
importance in many neurological disorders, particularly to monitor central nervous system …
importance in many neurological disorders, particularly to monitor central nervous system …
Antiretroviral penetration into the CNS and incidence of AIDS-defining neurologic conditions
Objective: The link between CNS penetration of antiretrovirals and AIDS-defining neurologic
disorders remains largely unknown. Methods: HIV-infected, antiretroviral therapy–naive …
disorders remains largely unknown. Methods: HIV-infected, antiretroviral therapy–naive …
Randomized trial of central nervous system–targeted antiretrovirals for HIV-associated neurocognitive disorder
Background. Antiretroviral (ARV) medications differentially penetrate across the blood-brain
barrier into central nervous system (CNS) tissues, potentially influencing their effectiveness …
barrier into central nervous system (CNS) tissues, potentially influencing their effectiveness …
Brain inflammation is a common feature of HIV-infected patients without HIV encephalitis or productive brain infection
E Tavazzi, D Morrison, P Sullivan… - Current HIV …, 2014 - ingentaconnect.com
HIV-associated neurocognitive disorders (HAND) describes different levels of
neurocognitive impairment, which are a common complication of HIV infection. The most …
neurocognitive impairment, which are a common complication of HIV infection. The most …
Neurocognitive impairment and HIV risk factors: a reciprocal relationship
Cognitive impairment among populations at risk for HIV poses a significant barrier to
managing risk behaviors. The impact of HIV and several cofactors, including substance …
managing risk behaviors. The impact of HIV and several cofactors, including substance …
Maraviroc-intensified combined antiretroviral therapy improves cognition in virally suppressed HIV-associated neurocognitive disorder
Objective: To investigate whether intensification of combined antiretroviral therapy (cART)
with the CC chemokine receptor type 5 (CCR5) entry inhibitor maraviroc leads to …
with the CC chemokine receptor type 5 (CCR5) entry inhibitor maraviroc leads to …
Structural gray and white matter changes in patients with HIV
M Küper, K Rabe, S Esser, ER Gizewski… - Journal of …, 2011 - Springer
In this cross-sectional study we used magnetic resonance imaging (MRI)-based voxel based
morphometry (VBM) in a sample of HIV positive patients to detect structural gray and white …
morphometry (VBM) in a sample of HIV positive patients to detect structural gray and white …
Does highly active antiretroviral therapy improve neurocognitive function? A systematic review
Highly active antiretroviral therapy (HAART) reduces the incidence of human
immunodeficiency virus (HIV) dementia (HAD), whereas the overall prevalence appears to …
immunodeficiency virus (HIV) dementia (HAD), whereas the overall prevalence appears to …
Neurocognitive dysfunction in the highly active antiretroviral therapy era
NZ Mothobi, BJ Brew - Current opinion in infectious diseases, 2012 - journals.lww.com
The prevalence of HAND remains high in the HAART era. Most studies point towards the
benefit of neuro-HAART in the prevention and treatment of HAND. The possible …
benefit of neuro-HAART in the prevention and treatment of HAND. The possible …
Fast implementation for normal mixed effects models with censored response
We propose an EM algorithm for computing the maximum likelihood and restricted maximum
likelihood for linear and nonlinear mixed effects models with censored response. In contrast …
likelihood for linear and nonlinear mixed effects models with censored response. In contrast …