Fish immunization has been carried out for over 50 years and is generally accepted as an
effective method for preventing a wide range of bacterial and viral diseases. Vaccination …

Designing Tomorrow's Vaccines | New England Journal of Medicine Skip to main content The
New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …

Klebsiella pneumoniae is an opportunistic gram-negative bacterium that causes nosocomial
infection in healthcare settings. Despite the high morbidity and mortality rate associated with …

Microbial pathogens have developed complex and efficient ways of counteracting and
evading innate and adaptive immune mechanisms. The strategies used by pathogens …

The COVID-19 pandemic has occupied the world agenda since December 2019. With no
effective treatment yet, vaccination seems to be the most effective method of prevention …

This paper reviews the current status of research and development of vaccines against
meningococcal disease due to Neisseria meningitidis, a major cause of severe meningitis …

Neisseria meningitidis causes endemic meningococcal disease worldwide. Serogroups B
and C are responsible for the majority of cases of meningococcal disease in Europe …

Background Burkholderia pseudomallei is an infectious agent causing severe disease
melioidosis resulting in pneumonia, fever, and acute septicemia in humans. B. pseudomallei …

Acinetobacter baumannii has emerged as one of major nosocomial pathogen and global
emergence of multidrug-resistant strains has become a challenge for developing effective …

The environmental conditions generated by war and characterized by poverty,
undernutrition, stress, difficult access to safe water and food as well as lack of environmental …