Aptamers or chemical antibodies are single-stranded DNA or RNA oligonucleotides that
bind proteins and small molecules with high affinity and specificity by recognizing tertiary or …

Precision medicine has recently emerged as a promising strategy for cancer therapy
because it not only specifically targets cancer cells but it also does not have adverse effects …

The study of myelodysplastic syndromes (MDS) in murine models has now indicated the
possible involvement of the bone marrow microenvironment in the generation of dysplastic …

This work reports the development of a biomimetic membrane-wrapped nanoparticle
(MWNP) platform for targeted chemotherapy of acute myeloid leukemia (AML). Doxorubicin …

Neoplastic and nonneoplastic mast cell disorders can cause diarrhea, nausea, and
abdominal pain that result from heightened release of mast cell mediators. Systemic …

Acute myeloid leukemia (AML) is a complex disease caused by deregulation of multiple
signaling pathways. Mutations in class III receptor tyrosine kinases (RTKs) have been …

The possible interaction between gene polymorphisms and risk of cancer progression is
very interesting. Polymorphisms in multi-drug resistance genes have an important role in …

Acute myeloid leukemia (AML) is the most lethal form of AML due to disease relapse. Cyclin
dependent kinase 8 (CDK8) is a serine/threonine kinase that belongs to the family of Cyclin …

La citometría de flujo (CMF) es una técnica de avanzada, altamente sensible y
automatizada, que se emplea para el inmunofenotipaje de las células normales y …

The maturation of B cells is a complex, multi-step process. During B cell differentiation,
errors can occur, leading to the emergence of aberrant versions of B cells that, finally …