Nitric oxide-mediated enhancement and reversal of resistance of anticancer therapies

E Hays, B Bonavida - Antioxidants, 2019 - mdpi.com
In the last decade, immune therapies against human cancers have emerged as a very
effective therapeutic strategy in the treatment of various cancers, some of which are resistant …

Nanocarriers targeting the diseases of the pancreas

N Demirtürk, E Bilensoy - European Journal of Pharmaceutics and …, 2022 - Elsevier
Diseases of the pancreas include acute and chronic pancreatitis, exocrine pancreatic
insufficiency, diabetes and pancreatic cancer. These pathologies can be difficult to treat due …

Low CD8+ T Cell Infiltration and High PD-L1 Expression Are Associated with Level of CD44+/CD133+ Cancer Stem Cells and Predict an Unfavorable Prognosis in …

YC Hou, YJ Chao, MH Hsieh, HL Tung, HC Wang… - Cancers, 2019 - mdpi.com
Cancer immunotherapy targeting immune checkpoints has exhibited promising clinical
outcomes in many cancers, but it offers only limited benefits for pancreatic cancer (PC) …

Self-assembled hyaluronan nanocapsules for the intracellular delivery of anticancer drugs

A Cadete, A Olivera, M Besev, PK Dhal, L Gonçalves… - Scientific Reports, 2019 - nature.com
Preparation of sophisticated delivery systems for nanomedicine applications generally
involve multi-step procedures using organic solvents. In this study, we have developed a …

Dietary crocin is protective in pancreatic cancer while reducing radiation-induced hepatic oxidative damage

HA Bakshi, MSA Zoubi, HL Faruck, AAA Aljabali… - Nutrients, 2020 - mdpi.com
Pancreatic cancer is one of the fatal causes of global cancer-related deaths. Although
surgery and chemotherapy are standard treatment options, post-treatment outcomes often …

Pectin-tannic acid nano-complexes promote the delivery and bioactivity of drugs in pancreatic cancer cells

SS Chauhan, AB Shetty, E Hatami, P Chowdhury… - Pharmaceutics, 2020 - mdpi.com
Pancreatic cancer (PanCa) is a lethal disease. Conventional chemotherapies for PanCa
offer severe systemic toxicities. Thus, the development of a successful nanomedicine-based …

TRIM11 suppresses ferritinophagy and gemcitabine sensitivity through UBE2N/TAX1BP1 signaling in pancreatic ductal adenocarcinoma

M Shang, L Weng, G Xu, S Wu, B Liu… - Journal of cellular …, 2021 - Wiley Online Library
Gemcitabine is first‐line chemotherapy for pancreatic cancer, however, the development of
resistance limits its effectiveness. The tripartite motif‐containing 11 (TRIM11) protein plays …

[HTML][HTML] Study of the antioxidant and anti-pancreatic cancer activities of Anchusa strigosa aqueous extracts obtained by maceration and ultrasonic extraction …

Z Chebaro, R Abdallah, A Badran, K Hamade… - Frontiers in …, 2023 - frontiersin.org
Pancreatic cancer is a highly aggressive malignancy and a leading cause of cancer-related
deaths worldwide. Moreover, the incidence and mortality rates for pancreatic cancer are …

[HTML][HTML] Oncogenic ADAM28 induces gemcitabine resistance and predicts a poor prognosis in pancreatic cancer

L Wei, JY Wen, J Chen, XK Ma, DH Wu… - World journal of …, 2019 - ncbi.nlm.nih.gov
BACKGROUND Pancreatic cancer is a major cause of cancer-related death, with a 5-year
overall survival rate being below 5%. The main causes of poor prognosis in pancreatic …

microRNA-26a represses pancreatic cancer cell malignant behaviors by targeting E2F7

L Wang, M Li, F Chen - Discover Oncology, 2021 - Springer
Dysregulation of microRNAs (miRNAs) exerts key roles in the development of pancreatic
cancer (PCa). miR-26a is reportedly a tumor suppressor in cancers. However, whether miR …