Positive end-expiratory pressure (PEEP) has been used during mechanical ventilation since
the first description of acute respiratory distress syndrome (ARDS). In the subsequent …

Background In patients with acute lung injury (ALI) and acute respiratory distress syndrome
(ARDS), mortality remains high. These patients require mechanical ventilation, which has …

Background Mechanical-ventilation strategies that use lower end-inspiratory (plateau)
airway pressures, lower tidal volumes (VT), and higher positive end-expiratory pressures …

Background Survival of patients with acute lung injury or the acute respiratory distress
syndrome (ARDS) has been improved by ventilation with small tidal volumes and the use of …

Background In the acute respiratory distress syndrome (ARDS), positive end-expiratory
pressure (PEEP) may decrease ventilator-induced lung injury by keeping lung regions open …

Context The need for lung protection is universally accepted, but the optimal level of positive
end-expiratory pressure (PEEP) in patients with acute lung injury (ALI) or acute respiratory …

Rationale: The hypothesis that lung collapse is detrimental during the acute respiratory
distress syndrome is still debatable. One of the difficulties is the lack of an efficient maneuver …

Rationale: The effects of high positive end-expiratory pressure (PEEP) strictly depend on
lung recruitability, which varies widely during acute respiratory distress syndrome (ARDS) …

Background Mechanical ventilation with a tidal volume (VT) of 6 mL/kg/predicted body
weight (PBW), to maintain plateau pressure (P plat) lower than 30 cmH 2 O, does not …

Abstract Acute Respiratory Distress Syndrome (ARDS) is a common entity in critical care.
ARDS is associated with many diagnoses, including trauma and sepsis, can lead to multiple …