Although many studies have been exploring the mechanisms driving NETs formation, much
less attention has been paid to the degradation and elimination of these structures. The …

Systemic lupus erythematosus (SLE) is a typical autoimmune disease with a complex
pathogenesis and genetic predisposition. With continued understanding of this disease, it …

The Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling
pathway is characterized by diverse immune regulatory systems involving cell proliferation …

The etiopathogenesis of systemic lupus erythematosus (SLE), a clinically heterogeneous
multisystemic syndrome that derives its name from the initial characterization of facial …

For most inflammatory skin diseases topical glucocorticosteroids and traditional oral
immunosuppressive drugs remain the principle treatment choices, but this has started to …

Abstract The European Journal of Immunology was launched 50 years ago, coinciding with
the discovery of many cytokines and growth factors and the emergence of an entirely new …

Lupus nephritis (LN) is a common manifestation of systemic lupus erythematosus that can
lead to irreversible renal impairment. Although the prognosis of LN has improved …

The endothelium is crucially important for the delivery of oxygen and nutrients throughout
the body under homeostatic conditions. However, it also contributes to pathology, including …

Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease
characterized by excessive inflammatory and immune responses and tissue damage …

Systemic lupus erythematosus (SLE) is a multisystem, chronic autoimmune disease where
treatment varies by patient and disease activity. Strong preclinical results and clinical …