The cancer burden continues to grow globally, and drug resistance remains a substantial
challenge in cancer therapy. It is well established that cancerous cells with clonal dysplasia …

Tumors are a heterogeneous group of cell masses originating in various organs or tissues.
The cellular composition of the tumor cell mass interacts in an intricate manner, influenced …

Glioblastoma (GBM) is the most aggressive primary central nervous system (CNS) tumor in
adults with dismal prognosis. Currently, the therapeutic interventions include gross total …

Results: ADAMTS8 expression was reduced in glioma tissues and cells. Higher expression
of ADAMTS8 was correlated with higher survival rates. ADAMTS8 was correlated with MMP2 …

First, I would like to thank my supervisor Dr Davide Danovi for allowing me to be part of his
group and for pushing me to be a more independent researcher. I am incredibly grateful for …

Özet Glioblastoma tüm onkolojide tedavisi en zor malignitelerden biridir. Gelişen olanaklara
rağmen glioblastoma tedavisinde istenilen sonuçlar gözlenmemektedir. Glioblastoma …