Novel spiro [chromanone-2, 4′-piperidine]-4-one derivatives as potential inhibitors of fatty acid synthesis in pathogens: Design, synthesis, and biological evaluation
SS Liu, D Zeng, TH Zhang, JH Hu, BX Yang… - European Journal of …, 2023 - Elsevier
Bacterial survival depends on membrane lipid homeostasis that enables to regulate lipid
composition to adapt and optimize their growth in diverse environments. Therefore, the …
composition to adapt and optimize their growth in diverse environments. Therefore, the …
[HTML][HTML] Discovery of novel 3-(piperazin-1-yl) propan-2-ol decorated carbazole derivatives as new membrane-targeting antibacterial agents
YG Ding, AQ Chen, N Wang, ZQ Long, HW Liu… - Arabian Journal of …, 2023 - Elsevier
The increasing resistance problems of pathogens have drastically reduced the efficiency of
existing drugs and agricultural chemicals, increasing the difficulty of preventing and …
existing drugs and agricultural chemicals, increasing the difficulty of preventing and …
[HTML][HTML] Editorial for the Special Issue—“Recent Advances of Novel Pharmaceutical Designs for Anti-Cancer Therapies”
B Biersack - International Journal of Molecular Sciences, 2023 - mdpi.com
Cancer is one of the leading causes of death worldwide, despite the promising
developments in terms of the curing and management of certain cancer types that have …
developments in terms of the curing and management of certain cancer types that have …
[HTML][HTML] Identification of acetylshikonin as a novel tubulin polymerization inhibitor with antitumor activity in human hepatocellular carcinoma cells
S Hu, Y Li, J Zhou, K Xu, Y Pang… - Journal of …, 2023 - ncbi.nlm.nih.gov
Background Microtubules are attractive targets for anticancer drugs. However, the
microtubule-targeting agents (MTAs) currently in clinical use exhibit inevitable drug …
microtubule-targeting agents (MTAs) currently in clinical use exhibit inevitable drug …