Summary Abstract Lacidipine (Caldine®, Lacimen®, Lacipil®, Midotens®, Motens®) is a
once-daily, orally-administered, lipophilic dihydropyridine calcium antagonist with an …

l-arginine is the substrate used by NO synthase to produce the vasodilator NO. However, in
several human diseases, such as hyperhomocysteinemia, diabetes mellitus, and …

Nitric oxide (NO) is an important signaling molecule that plays a key role in maintaining
vascular homeostasis. Dinitrosyl iron complexes (DNICs) generating NO are widely used to …

A selective, rapid and sensitive ultra-performance liquid chromatography–tandem mass
spectrometry (UPLC–ESI-MS/MS) method was developed and validated for the …

A simple, novel, rapid and sensitive supercritical fluid chromatography–tandem mass
spectrometry (SFC-MS/MS) method was developed and validated for the determination of …

The aim of our study was to evaluate potential differences in the concentration of
biochemical markers of endothelial dysfunction between essential hypertension, endocrine …

Background/aims: Calcium channel blockers are increasingly used for the treatment of
hypertension. Menopause and hypertension are both important risk factors for liver damage …

A simple, sensitive and rapid liquid chromatographic/electrospray ionization tandem mass
spectrometric method was developed and validated for the quantification of lacidipine in …

Вступ. Вибір лікування артеріальної гіпертензії (АГ) базується на попередньому досвіді
застосування препаратів у конкретного пацієнта, профілі серцево-судинного ризику …

Purpose In a randomised, double-blind trial, we investigated effects of lacidipine on clinic
and ambulatory blood pressure (BP) and arterial stiffness in patients with mild-to-moderate …