Targeting oxidative stress and inflammatory response for blood–brain barrier protection in intracerebral hemorrhage
S Chen, L Li, C Peng, C Bian, PE Ocak… - Antioxidants & redox …, 2022 - liebertpub.com
Significance: Blood–brain barrier (BBB) disruption is a major pathological change after
intracerebral hemorrhage (ICH) and is both the cause and result of oxidative stress and of …
intracerebral hemorrhage (ICH) and is both the cause and result of oxidative stress and of …
The melanocortin pathway and control of appetite-progress and therapeutic implications
G Baldini, KD Phelan - Journal of Endocrinology, 2019 - joe.bioscientifica.com
The initial discovery that ob/ob mice become obese because of a recessive mutation of the
leptin gene has been crucial to discover the melanocortin pathway to control appetite. In the …
leptin gene has been crucial to discover the melanocortin pathway to control appetite. In the …
TREM2 activation attenuates neuroinflammation and neuronal apoptosis via PI3K/Akt pathway after intracerebral hemorrhage in mice
S Chen, J Peng, P Sherchan, Y Ma, S Xiang… - Journal of …, 2020 - Springer
Background Neuroinflammation is an important host defense response to secondary brain
injury after intracerebral hemorrhage (ICH). Triggering receptor expressed on myeloid cells …
injury after intracerebral hemorrhage (ICH). Triggering receptor expressed on myeloid cells …
Irisin ameliorates neuroinflammation and neuronal apoptosis through integrin αVβ5/AMPK signaling pathway after intracerebral hemorrhage in mice
Y Wang, M Tian, J Tan, X Pei, C Lu, Y Xin… - Journal of …, 2022 - Springer
Background Neuroinflammation is a crucial factor in the development of secondary brain
injury after intracerebral hemorrhage (ICH). Irisin is a newly identified myokine that confers …
injury after intracerebral hemorrhage (ICH). Irisin is a newly identified myokine that confers …
Puerarin attenuates oxidative stress and ferroptosis via AMPK/PGC1α/Nrf2 pathway after subarachnoid hemorrhage in rats
Y Huang, H Wu, Y Hu, C Zhou, J Wu, Y Wu, H Wang… - Antioxidants, 2022 - mdpi.com
Puerarin was shown to exert anti-oxidative and anti-ferroptosis effects in multiple diseases.
The goal of this study was to explore the neuroprotective effect of puerarin on early brain …
The goal of this study was to explore the neuroprotective effect of puerarin on early brain …
Urolithin A attenuates memory impairment and neuroinflammation in APP/PS1 mice
Z Gong, J Huang, B Xu, Z Ou, L Zhang, X Lin… - Journal of …, 2019 - Springer
Background Alzheimer's disease (AD) is a progressive neurodegenerative disorder
characterized by an abnormal accumulation of amyloid-β (Aβ) plaques, neuroinflammation …
characterized by an abnormal accumulation of amyloid-β (Aβ) plaques, neuroinflammation …
Environment and gene association with obesity and their impact on neurodegenerative and neurodevelopmental diseases
MT Flores-Dorantes, YE Díaz-López… - Frontiers in …, 2020 - frontiersin.org
Obesity is a multifactorial disease in which environmental conditions and several genes play
an important role in the development of this disease. Obesity is associated with …
an important role in the development of this disease. Obesity is associated with …
Ezetimibe attenuates oxidative stress and neuroinflammation via the AMPK/Nrf2/TXNIP pathway after MCAO in rats
J Yu, W Wang, N Matei, X Li, J Pang… - Oxidative Medicine …, 2020 - Wiley Online Library
Oxidative stress and neuroinflammation play essential roles in ischemic stroke‐induced
brain injury. Previous studies have reported that Ezetimibe (Eze) exerts antioxidative stress …
brain injury. Previous studies have reported that Ezetimibe (Eze) exerts antioxidative stress …
[HTML][HTML] Melanocortin 1 receptor attenuates early brain injury following subarachnoid hemorrhage by controlling mitochondrial metabolism via AMPK/SIRT1/PGC-1α …
Mitochondria-mediated oxidative stress and apoptosis contribute greatly to early brain injury
(EBI) following subarachnoid hemorrhage (SAH). This study hypothesized that activation of …
(EBI) following subarachnoid hemorrhage (SAH). This study hypothesized that activation of …
Microglia and macrophage phenotypes in intracerebral haemorrhage injury: therapeutic opportunities
The prognosis of intracerebral haemorrhage continues to be devastating despite much
research into this condition. A prominent feature of intracerebral haemorrhage is …
research into this condition. A prominent feature of intracerebral haemorrhage is …