Flavonoids as potential agents in the management of type 2 diabetes through the modulation of α-amylase and α-glucosidase activity: a review

C Proença, D Ribeiro, M Freitas… - Critical Reviews in Food …, 2022 - Taylor & Francis
Abstract Type 2 diabetes (T2D) is one of the most prevalent metabolic diseases worldwide
and is characterized by increased postprandial hyperglycemia (PPHG). α-Amylase and α …

[HTML][HTML] Insulin resistance and diabetes mellitus in Alzheimer's disease

J Burillo, P Marqués, B Jiménez, C González-Blanco… - Cells, 2021 - mdpi.com
Type 2 diabetes mellitus is a progressive disease that is characterized by the appearance of
insulin resistance. The term insulin resistance is very wide and could affect different proteins …

Obesity in people living with type 1 diabetes

B Van der Schueren, D Ellis, RN Faradji… - The Lancet Diabetes & …, 2021 - thelancet.com
Although type 1 diabetes is traditionally considered a disease of lean people, overweight
and obesity are becoming increasingly more common in individuals with type 1 diabetes …

Nutrient element decorated polyetheretherketone implants steer mitochondrial dynamics for boosted diabetic osseointegration

H Wang, X Fu, J Shi, L Li, J Sun, X Zhang… - Advanced …, 2021 - Wiley Online Library
As a chronic metabolic disease, diabetes mellitus (DM) creates a hyperglycemic micromilieu
around implants, resulting inthe high complication and failure rate of implantation because …

[HTML][HTML] The effects of curcumin on diabetes mellitus: a systematic review

LT Marton, LM Pescinini-e-Salzedas… - Frontiers in …, 2021 - frontiersin.org
Diabetes mellitus (DM) is an ensemble of metabolic conditions that have reached pandemic
proportions worldwide. Pathology's multifactorial nature makes patient management …

[HTML][HTML] NLRP3 inflammasome at the interface of inflammation, endothelial dysfunction, and type 2 diabetes

IM Gora, A Ciechanowska, P Ladyzynski - Cells, 2021 - mdpi.com
Type 2 diabetes mellitus (T2DM), accounting for 90–95% cases of diabetes, is characterized
by chronic inflammation. The mechanisms that control inflammation activation in T2DM are …

[HTML][HTML] Stress-induced β cell early senescence confers protection against type 1 diabetes

H Lee, GS Sahin, CW Chen, S Sonthalia, SM Cañas… - Cell Metabolism, 2023 - cell.com
During the progression of type 1 diabetes (T1D), β cells are exposed to significant stress
and, therefore, require adaptive responses to survive. The adaptive mechanisms that can …

[HTML][HTML] Persistent or transient human β cell dysfunction induced by metabolic stress: specific signatures and shared gene expression with type 2 diabetes

L Marselli, A Piron, M Suleiman, ML Colli, X Yi… - Cell Reports, 2020 - cell.com
Pancreatic β cell failure is key to type 2 diabetes (T2D) onset and progression. Here, we
assess whether human β cell dysfunction induced by metabolic stress is reversible, evaluate …

Closed-loop diabetes minipatch based on a biosensor and an electroosmotic pump on hollow biodegradable microneedles

X Luo, Q Yu, Y Liu, W Gai, L Ye, L Yang, Y Cui - ACS sensors, 2022 - ACS Publications
Developing a miniaturized, low-cost, and smart closed-loop system for diabetes could
significantly improve life quality and benefit millions of people. Conventional closed-loop …

[HTML][HTML] Pathological β-cell endoplasmic reticulum stress in type 2 diabetes: current evidence

N Shrestha, E De Franco, P Arvan… - Frontiers in …, 2021 - frontiersin.org
The notion that in diabetes pancreatic β-cells express endoplasmic reticulum (ER) stress
markers indicative of increased unfolded protein response (UPR) signaling is no longer in …