Candida albicans biofilms and polymicrobial interactions

NO Ponde, L Lortal, G Ramage, JR Naglik… - Critical reviews in …, 2021 - Taylor & Francis
Candida albicans is a common fungus of the human microbiota. While generally a harmless
commensal in healthy individuals, several factors can lead to its overgrowth and cause a …

Development and regulation of single- and multi-species Candida albicans biofilms

MB Lohse, M Gulati, AD Johnson… - Nature Reviews …, 2018 - nature.com
Candida albicans is among the most prevalent fungal species of the human microbiota and
asymptomatically colonizes healthy individuals. However, it is also an opportunistic …

Candida sp. Infections in Patients with Diabetes Mellitus

CF Rodrigues, ME Rodrigues, M Henriques - Journal of clinical medicine, 2019 - mdpi.com
Candidiasis has increased substantially worldwide over recent decades and is a significant
cause of morbidity and mortality, especially among critically ill patients. Diabetes mellitus …

Candida albicans Biofilms and Human Disease

CJ Nobile, AD Johnson - Annual review of microbiology, 2015 - annualreviews.org
In humans, microbial cells (including bacteria, archaea, and fungi) greatly outnumber host
cells. Candida albicans is the most prevalent fungal species of the human microbiota; this …

Antifungal therapy: new advances in the understanding and treatment of mycosis

L Scorzoni, ACA de Paula e Silva, CM Marcos… - Frontiers in …, 2017 - frontiersin.org
The high rates of morbidity and mortality caused by fungal infections are associated with the
current limited antifungal arsenal and the high toxicity of the compounds. Additionally …

Molecular mechanisms of antimicrobial tolerance and resistance in bacterial and fungal biofilms

H Van Acker, P Van Dijck, T Coenye - Trends in microbiology, 2014 - cell.com
The formation of microbial biofilms is an important reason for failure of antimicrobial therapy.
However, the molecular mechanisms underlying the survival of biofilm cells are still not …

Mechanisms of Candida Biofilm Drug Resistance

HT Taff, KF Mitchell, JA Edward, DR Andes - Future microbiology, 2013 - Taylor & Francis
Candida commonly adheres to implanted medical devices, growing as a resilient biofilm
capable of withstanding extraordinarily high antifungal concentrations. As currently available …

Fungal biofilm resistance

G Ramage, R Rajendran, L Sherry… - International journal of …, 2012 - Wiley Online Library
Fungal biofilm infections have become increasingly recognised as a significant clinical
problem. One of the major reasons behind this is the impact that these have upon treatment …

Genetic control of Candida albicans biofilm development

JS Finkel, AP Mitchell - Nature Reviews Microbiology, 2011 - nature.com
Candida species cause frequent infections owing to their ability to form biofilms—surface-
associated microbial communities—primarily on implanted medical devices. Increasingly …

A recently evolved transcriptional network controls biofilm development in Candida albicans

CJ Nobile, EP Fox, JE Nett, TR Sorrells, QM Mitrovich… - Cell, 2012 - cell.com
A biofilm is an organized, resilient group of microbes in which individual cells acquire
properties, such as drug resistance, that are distinct from those observed in suspension …