Allosteric transitions in hemoglobin revisited

N Shibayama - Biochimica et Biophysica Acta (BBA)-General Subjects, 2020 - Elsevier
Background Human hemoglobin is an allosteric protein that exerts exquisite control over
ligand binding through large-scale conformational changes. The two-state model without …

Diffracted X-ray Tracking for Observing the Internal Motions of Individual Protein Molecules and Its Extended Methodologies

YC Sasaki - International Journal of Molecular Sciences, 2023 - mdpi.com
In 1998, the diffracted X-ray tracking (DXT) method pioneered the attainment of molecular
dynamics measurements within individual molecules. This breakthrough revolutionized the …

Diffracted X-ray blinking tracks single protein motions

H Sekiguchi, M Kuramochi, K Ikezaki, Y Okamura… - Scientific Reports, 2018 - nature.com
Single molecule dynamics studies have begun to use quantum probes. Single particle
analysis using cryo-transmission electron microscopy has dramatically improved the …

Asymmetry in the function and dynamics of the cytosolic group II chaperonin CCT/TRiC

YY Yamamoto, Y Uno, E Sha, K Ikegami, N Ishii… - PLoS …, 2017 - journals.plos.org
The eukaryotic group II chaperonin, the chaperonin-containing t-complex polypeptide 1
(CCT), plays an important role in cytosolic proteostasis. It has been estimated that as much …

Dynamic 3D visualization of active protein′ s motion using diffracted X-ray tracking

H Sekiguchi, YC Sasaki - Japanese Journal of Applied Physics, 2019 - iopscience.iop.org
Diffracted X-ray tracking (DXT) is one of the single-molecule techniques for investigating
intra-molecule dynamics of functional proteins at the single-molecule level with nanocrystal …

Overview of “2SEA Frontiers of Synchrotron Radiation Biophysics” session of symposia in the 57th Annual Meeting of Biophysical Society of Japan

H Iwamoto, H Sekiguchi - Biophysical Reviews, 2020 - Springer
This symposium session was intended to introduce to the society members the most recent
achievements done by using SPring-8, the large-scale 3rd-generation synchrotron facility in …