Hippocampus is the significant component of the limbic lobe, which is further subdivided into
the dentate gyrus and parts of Cornu Ammonis. It is the crucial region for learning and …

BACKGROUND The idea that memory is stored as enduring changes in the brain dates
back at least to the time of Plato and Aristotle (circa 350 BCE), but its scientific articulation …

Neuronal ensembles that hold specific memory (memory engrams) have been identified in
the hippocampus, amygdala, or cortex. However, it has been hypothesized that engrams of …

Synapse remodeling is essential to encode experiences into neuronal circuits. Here, we
define a molecular interaction between neurons and microglia that drives experience …

While initial encoding of contextual memories involves the strengthening of hippocampal
circuits, these memories progressively mature to stabilized forms in neocortex and become …

Network dynamics have been proposed as a mechanistic substrate for the information
transfer across cortical and hippocampal circuits. However, little is known about the …

Throughout our lifespan, new sensory experiences and learning continually shape our
neuronal circuits to form new memories. Plasticity at the level of synapses has been …

Humans and animals have the ability to continually acquire, fine-tune, and transfer
knowledge and skills throughout their lifespan. This ability, referred to as lifelong learning, is …

Modern society faces major environmental problems, but there are many difficulties in
studying the nature–human relationship from an integral psychosocial perspective. We …

The dentate gyrus (DG) has a key role in hippocampal memory formation. Intriguingly, DG
lesions impair many, but not all, hippocampus-dependent mnemonic functions, indicating …